Browsing Department of Medical BioSciences by Title
Now showing items 163-182 of 230
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Paediatric non-alcoholic fatty pancreas disease and aortic intimal medial thickness: A study identifying potential fatty infiltration of the pancreas and its association with aortic IMT in children exposed to teratogens during pregnancy
(University of the Western Cape, 2020)The incidence of non-communicable diseases is increasing worldwide, with South Africa being no exception. Non-communicable diseases are classified as non-infectious and are often referred to as lifestyle diseases as they ... -
The paracrine effect of normoxic and hypoxic cancer secretions on blood-brain barrier endothelial cells
(University of the Western Cape, 2022)Cancer is the most common leading cause of death worldwide. Glioblastoma and breast cancer are the most aggressive solid tumour. The survival rate of these tumours depends on their ability to progress and spread. These ... -
The phenomenon of skin lightening among young adults, and the effect of selected plant extracts on tyrosinase and melanogenesis activity
(University of the Western Cape, 2023)Skin lightening practice refers to the use of skin lightening products to achieve a fairer skin complexion. This is common practice among people of several Asian, North American, South American countries. On the African ... -
Phenotypic and molecular characteristics of Methicillin-resistant Staphylococcus Aureus isolates from stored patient samples in Misurata hospitals and poultry from commercial markets, Libya
(University of the Western Cape, 2019)The emergence of virulent and drug-resistant bacterial strains such as methicillin-resistant Staphylococcus aureus (MRSA) is a global public health burden. The World Health Organization (WHO) has placed MRSA and ... -
Phylogeography and speciation in the genus arthroleptella
(2009)Moss frogs are restricted to permanently moist terrestrial habitats in the south-western Cape Fold Mountains. There is a very close association between Arthroleptella distribution and Table Mountain Sandstone. Suitable ... -
The possible effect of Hypoxis hemerocalledia (African potato) on blood glucose levels : an in vitro study
(University of the Western Cape, 2015)The plant Hypoxis hemerocallidea, also known as the African potato, is commonly used as a traditional medicine to treat diabetes in South Africa. The mechanism by which it lowers blood glucose levels is not known. The ... -
Potamanautes warreni biomarker assays to monitor silver nanomaterial contaminants in aquatic environments
(University of the Western Cape, 2016)There has been extensive growth in nanoscale technology in the last few decades to such a degree that nanomaterials (NMs) have become a constituent in a wide range of manufactured commercial and domestic products. This ... -
Potamonautes spp. As a bioindicator for oestrogenic endocrine disrupting chemicals
(University of the Western Cape, 2017)Environmental pollutants, such as endocrine disrupting chemicals (EDCs), are a health concern as they can adversely affect animal health by interfering with the normal function of hormones. Oestrogenic EDCs can cause ... -
Potential anti-melanogenic effects of selected South African plants on b16 melanoma cells
(University of the Western Cape, 2019)Dyspigmentation is one of the commonest dermatological presenting complaints from patients, particularly hyperpigmentation. Hyperpigmentation can cause dangerous psychological and emotional impact on self-perception and ... -
Potential neuroprotective effects of fermented rooibos herbal tea in a rat model of ischemic brain injury
(University of the Western Cape, 2015)Stroke is the third leading cause of death in South Africa, killing about 240 people a day and leaving survivors with residual disabilities. There is no clinically approved neuroprotective agent for stroke at the moment ... -
The potential neuroprotective effects of two South African plant extracts in hydrogen peroxide-induced neuronal toxicity
(University of the Western Cape, 2018)Background: Oxidative stress induced by reactive oxygen species has been strongly associated with many neurodegenerative diseases (NDDs) and many medicinal plant-derived products have been reported to exert potent antioxidant ... -
The potential therapeutic role of palm oil on prostate cancer
(University of the Western Cape, 2020)Prostate cancer is one of the heterogeneous groups of neoplastic diseases originating from the reproductive system of the male naming, the prostate gland. In the west, prostate cancer is the most common cancer affecting ... -
Premature aging of the lungs of the offspring induced by maternal nicotine exposure during gestation and lactation: protective effects of tomato juice
(University of the Western Cape, 2012)exposed to nicotine through the blood and the milk of the mother. Nicotine is thus expected to interact with the developing fetus and the offspring of mothers who smoke or use NRT for smoking cessation, resulting in the ... -
Prevalence and characterization of Gardnerella vaginalis in pregnant mothers with a history of preterm delivery
(University of the Western Cape, 2012)Risk factors such as intrauterine and vaginal infection put pregnant women at risk for delivering preterm. Bacterial vaginosis (BV) is a polymicrobial clinical syndrome commonly diagnosed in women of reproductive age, with ... -
The Prevalence of Members of the “Red Complex” in Pregnant Women as Revealed by PCR and BANA Hydrolysis.
(University of the Western Cape, 2005)Increased levels of oestrogen and progesterone during pregnancy may lead to periodontal disease. The anaerobic Gram-negative bacteria called red complex (Porphyromonas gingivalis, Tannerella forsythensis and Treponema ... -
The prevalence, risk factors and serotypes of GBS in Libyan women at labour and the rate of vertical transmission of GBS from mother to infant
(University of the Western Cape, 2022)Group B Streptococcus (GBS) also known as Streptococcus agalactia, is one of the most important causes of serious neonatal infections. Early detection of GBS colonisation in the mother is thus of primary importance to ... -
Production of cytokines in human whole blood after incubation with the nucleocapsid protein of the NL63 Coronavirus
(University of the Western Cape, 2012-11)The Coronaviridae family consists of RNA viruses within the order Nidovirales. The family is classified into two genera, namely the corona- and toroviruses. Coronaviruses are enveloped, single stranded, positive sense ... -
Protein expression and antifungal effect of fluconazole-resistant Candida species following effective in vitro treatment with K21, a novel antifungal agent
(University of Western Cape, 2019)Background: Oropharyngeal candidiasis, caused by the fungus Candida, is the most common opportunistic infection affecting the quality of life of immunocompromised patients. Fluconazole is widely used as the first line ... -
Proteome profiling as tool to determine the effectiveness of traditional Africa therapies for Type 2 diabetes mellitus
(University of the Western Cape, 2022)Type 2 diabetes mellitus (T2DM) involves multiple organ dysfunction accompanied by a chronic inflammatory state and oxidative stress resulting from a combination of factors such as hyperglycaemia and dyslipidaemia. Although ... -
A quantitative and qualitative assessment of dental aerosols within a dental clinical unit: An avenue for the transmission of resistant nosocomial infection.
(University of Western Cape, 2020)Introduction: Nosocomial infections are infections that occur 48 hours after receiving care for an unrelated condition in a clinic or a hospital environment, many of which are resistant to at least one of the drugs most ...