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The association between environmental exposures during childhood and the subsequent development of crohn's disease in the Western Cape
(University of the Western Cape, 2015)
Background: A subtype of inflammatory bowel disease, Crohn’s disease is thought to represent a complex interaction between environmental factors, a defective immune system, the gastrointestinal microbiome and genetic ...
Ursolic acid and oleanolic acid as novel therapeutic agents in breast cancer
(University of the Western Cape, 2015)
Breast cancer is one of the most common cancers among women in South Africa and the second leading cause of cancer death after lung cancer. According to the American Cancer Society 2015, women have a 12% chance of developing ...
The effects of Ethanol and Aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)
(University of the Western Cape, 2015)
The blood brain barrier (BBB) is a signaling interface between the blood and the central nervous system (CNS), which prohibits the entry of harmful blood-borne substances into the brain micro-environment, thus maintaining ...
The possible effect of Hypoxis hemerocalledia (African potato) on blood glucose levels : an in vitro study
(University of the Western Cape, 2015)
The plant Hypoxis hemerocallidea, also known as the African potato, is commonly
used as a traditional medicine to treat diabetes in South Africa. The mechanism by
which it lowers blood glucose levels is not known. The ...
Comparative in vitro study of the anti-cancer effect of apricot and peach kernel extracts on human colon cancer cells
(University of the Western Cape, 2015)
Amygdalin, a controversial anti-cancer agent, is a cyanogenic glycoside plant compound found in apricot and peach kernels. Both amygdalin and its patented form, Laetrile®, have been promoted and sold as "vitamin B-17", ...
Antibacterial activity of some South African plant extracts against streptococcus mutans
(University of the Western Cape, 2015)
Good oral health has a major influence on the general quality of life and well-being. Several chronic and systemic diseases have been attributed to poor oral health. With the increasing incidence of oral diseases, the ...
The effects of ethanol and aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)
(University of the Western Cape, 2015)
The blood brain barrier (BBB) is a signaling interface between the blood and the
central nervous system (CNS), which prohibits the entry of harmful blood-borne
substances into the brain micro-environment, thus maintaining ...
Modulation of colon carcinogenesis by dietary ω-6/ω-3 fatty acid ratios : a chemopreventive strategy?
(University of the Western Cape, 2015)
The aim of this study was to determine whether dietary fats constituting specific ω-6/ω-3 fatty acids (FA) ratio has chemopreventive modulating effects on the development of colon cancer. Western diets intake of saturated ...
Effects of Libyan traditional plants on the reproductive system of male and female rats
(University of the Western cape, 2015)
In different parts of the world, medicinal plants have demonstrated a lot of health benefits to mankind and remains an important source for the discovery of new bio-active compounds. Libya is a typical example of a country ...
An in vitro investigation of the effects of camellia sinensis and aspalathus linearis on benign (RPWE 1) and malignant (LNCaP) prostate cell lines
(University of the Western Cape, 2015)
The prostate is prone to three pathological processes that include inflammation, benign prostate hyperplasia (BPH) and tumors. According to the center for Disease and Control 1999-2012 report, prostate cancer is the second ...