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The assessment of Namibian water resources for endocrine disruptors
(University of the Western Cape, 2018)
Namibia is the driest sub-Saharan country in Africa and it is characterised by low
and variable rainfall. As a result, potable water in this mostly semi-arid country is
considered an extremely valuable resource. Given ...
Seasonal differences in semen characteristics and sperm functionality in Tankwa goats
(University of the Western Cape, 2018)
Tankwa goats have been free-ranging in the Tankwa Karoo National Park in the Northern Cape for more than 80 years. A genetic study concluded that these feral goats are a unique genetic resource compared to other goat breeds ...
The effect of methamphetamine on the blood-testis barrier
(University of the Western Cape, 2018)
Introduction
The blood-testis barrier (BTB) is formed by tight junctions between adjacent Sertoli cells. The barrier formed by these tight junction helps to create a specialized environment for spermatogenesis and provide ...
The antifungal effect of Salvadora persica and Euclea natalensis on Candida isolates from Libyan patients with type 2 Diabetes mellitus.
(University of the Western Cape, 2018)
Improved oral hygiene plays a vital role on quality of health and well-being of diabetic
patients. Poor oral health leads to an increased incidence of oral diseases, particularly
oral candidiasis. The emergence and global ...
Formulation and evaluation of the biocompatibility of chitosan-dextran nanoparticles using a blood-brain barrier model
(University of the Western Cape, 2018)
Central nervous system (CNS) infections are a therapeutic challenge. This is partly due to insufficient drug penetration across the blood-brain barrier (BBB). The BBB is a specialized, highly selective, metabolically active ...
Investigating the anti-cancer activity of novel phenothiazines in glioblastoma
(University of the Western Cape, 2018)
Glioblastoma multiforme (GBM) remains the most malignant of all primary adult brain tumours. It is a highly invasive and vascularized neoplasm with limited treatment options and very low survival rate. GBM tumours are ...
Identification and characterisation of cephalosporins and carbapenem-resistant Klebsiella pneumoniae isolates from Misrata, Libya
(University of the Western Cape, 2018)
Background: Extended-spectrum beta-lactamase-producing (ESBL) and carbapenemaseproducing
Gram-negative bacilli showing resistance to cephalosporins and carbapenems
respectively, have been reported from several countries ...
Medicinal uses of Galenia africana: A study of the antimicrobial, antifungal and anticancer properties
(University of the Western Cape, 2018)
Medicinal uses of Galenia africana: A study of the antimicrobial, antifungal and anticancer properties
Over the years, microorganisms have become resistant to commonly used antimicrobial agents leading to multidrug resistance. ...
The potential neuroprotective effects of two South African plant extracts in hydrogen peroxide-induced neuronal toxicity
(University of the Western Cape, 2018)
Background: Oxidative stress induced by reactive oxygen species has been strongly associated with many neurodegenerative diseases (NDDs) and many medicinal plant-derived products have been reported to exert potent antioxidant ...
The role of high-risk human papillomavirus in periocular cancers
(University of the Western Cape, 2018)
PURPOSE: High risk human papillomavirus (HR-HPV) is well established as a causative agent of squamous cell carcinoma (SCC) of the orophaynx. HR-HPV has also been reported in periocular cancers and precancers, but controversy ...