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Phenotypic and molecular characteristics of Methicillin-resistant Staphylococcus Aureus isolates from stored patient samples in Misurata hospitals and poultry from commercial markets, Libya
(University of the Western Cape, 2019)
The emergence of virulent and drug-resistant bacterial strains such as methicillin-resistant
Staphylococcus aureus (MRSA) is a global public health burden. The World Health
Organization (WHO) has placed MRSA and ...
An evaluation of cancer biomarkers in normal ovarian epithelial cells and ovarian cancer cell lines
(University of the Western Cape, 2019)
Introduction: Globally, there are over 190,000 new reported cases of ovarian cancers per annum. This comprises 3% to 4% of all cancers in women. Ovarian cancer is one of the leading causes of deaths in women. Ovarian cancer ...
The effect of maternal exposure to alcohol and nicotine on pancreas and kidney size, aorta and carotid intima thickness and visceral fat in their children.
(University of Western Cape, 2019)
In utero exposure to teratogens, increasing urbanization, rapid nutritional transition from poverty to affluence, adoption of a Western-style diet and physical inactivity have contributed to the growing obesity epidemic ...
Evaluating the neuroprotective effects of fermented rooibos herbal tea in Wistar rats exposed to bisphenol-A during gestation and lactation
(University of the Western Cape, 2019)
Exposure to endocrine-disrupting chemicals as bisphenol A (BPA) during gestation and early postnatal life is known to disrupt normal developmental processes and alter the body’s endocrine system leading to deleterious ...
Evaluation of sperm functionality in non-human primates, focussing on sperm capacitation
(University of the Western Cape, 2019)
The incidence of male infertility is increasing, with up to 50% of infertile males having “unexplained” (idiopathic) infertility. Newly developed molecular techniques have great value in detecting subtle causes of male ...
Potential anti-melanogenic effects of selected South African plants on b16 melanoma cells
(University of the Western Cape, 2019)
Dyspigmentation is one of the commonest dermatological presenting complaints from patients, particularly hyperpigmentation. Hyperpigmentation can cause dangerous psychological and emotional impact on self-perception and ...
Effects of graphene oxide nanoparticles on the immune system biomarkers produced by RAW 264.7
(University of the Western Cape, 2019)
Graphene oxide (GO) is a single carbon layer, oxygen bearing graphene derivative, containing hydroxyl and carboxyl groups. Graphene oxide nanoparticles (GONPs) are promising nanomaterials for a variety of applications such ...
Protein expression and antifungal effect of fluconazole-resistant Candida species following effective in vitro treatment with K21, a novel antifungal agent
(University of Western Cape, 2019)
Background: Oropharyngeal candidiasis, caused by the fungus Candida, is the most common
opportunistic infection affecting the quality of life of immunocompromised patients. Fluconazole
is widely used as the first line ...
Mercury leaching from dental amalgam fillings and its association with urinary zinc
(University of the Western Cape, 2019)
Mercury (Hg) is an example of a toxic metal that is not essential for nutrition. It exists in organic and inorganic forms in seafood and vapour from dental amalgam fillings respectively. Elemental mercury (Hg0) from dental ...