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Now showing items 1885-1904 of 8878
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Design, Synthesis and Evaluation of Indole Derivatives as Multifunctional Agents against Alzheimer's disease.
(University of the Western Cape, 2017)Alzheimer's disease (AD) is an age related neurodegenerative disorder characterised by progressive memory loss and cognitive impairment. It is one of several neurodegenerative disorders occurring as a result of a process ... -
Designing a community reintegration programme for individuals with a traumatic spinal cord injury in the Cape Metropolitan area
(University of the Western Cape, 2018)Spinal cord injury (SCI) is a devastating condition often affecting young and healthy individuals around the world. This debilitating condition not only creates enormous physical and emotional suffering to individuals but ... -
Designing and determining the effectiveness of a health promotion programme for clients with type 2 diabetes mellitus from an urban South African community
(University of the Western Cape, 2013)Diabetes mellitus, an international pandemic, is one of the greatest threats to global public health. It is estimated that 70% of patients with diabetes are living in developing countries. Since the inception of the Primary ... -
Designing industrial image processing applications for warehouse management in South Africa
(University of Western Cape, 2021)With conclusive evidence from multiple research studies it is evident that the lack of real time information flows in Warehouse Management (WM) operations leads to rigid, un-optimised supply chains. Industrial Image ... -
Designing next generation high energy density lithium-ion battery with manganese orthosilicate-capped alumina nanofilm
(University of the Western Cape, 2015)In the wide search for advanced materials for next generation lithium-ion batteries, lithium manganese orthosilicate, Li₂MnSiO₄ is increasingly gaining attention as a potential cathode material by virtue of its ability to ... -
Designing, developing and evaluating a management information system for vitamin a supplementation programme managers in the Eastern Cape through action research
(University of the Western Cape, 2003)Periodic high doses of vitamin A supplementation has been demonstrated to have a dramatic impact on vitamin A status and general health of children, significantly improving child survival. The Eastern Cape Department of ... -
Destination attributes that attract international tourists to Cape Town
(University of the Western Cape, 2005)The purpose of this study is twofold. The first purpose is to identify Cape Town’s important destination attributes. Secondly one needs to examine how and to what extent Cape Town’s important destination attributes impact ... -
Detecting Baryon Acoustic Oscillations with HI Intensity Mapping using MeerKAT
(University of the Western Cape, 2019)Future radio surveys as the Square Kilometer Array (SKA) and its precursor, the "Meer" Karoo Array Telescope (MeerKAT), will map the Neutral Hydrogen (HI) in large areas of the sky using the intensity mapping (IM). HI ... -
Detecting Galaxies in the Epoch of Reionization
(University of the Western Cape, 2017)The aim of this project was to develop a technique that allows us to measure the redshift of radio galaxies in the Epoch of Reionization. We achieved this by constructing a parameterization of the 21-cm absorption feature ... -
Detecting patterns of upwelling variability in Eastern Boundary Upwelling Systems with special emphasis on the Benguela region
(University of Western Cape, 2020)Coastal upwelling is one of the most important oceanographic processes relating to ecosystem function at local and global spatial scales. To better understand how changes in upwelling trends may occur in the face of ongoing ... -
Detecting patterns of upwelling variability in Eastern Boundary Upwelling Systems with special emphasis on the Benguela region
(University of the Western Cape, 2020)Coastal upwelling is one of the most important oceanographic processes relating to ecosystem function at local and global spatial scales. To better understand how changes in upwelling trends may occur in the face of ongoing ... -
The detection of meningococcal disease through identification of antimicrobial peptides using an in silico model creation
(University of the Western Cape, 2019)Neisseria meningitidis (the meningococcus), the causative agent of meningococcal disease (MD) was identified in 1887 and despite effective antibiotics and partially effective vaccines, Neisseria meningitidis (N. meningitidis) ... -
Detection of phycotoxins along the South African coast: a comparison of three different biological assay systems and instrumental analysis by high performance liquid chromatography
(University of the Western Cape, 1998)In recent years, harmful algal blooms have been of growing concern in many parts of the world. These blooms often result in deterioration in water quality, large-scale mortalities in marine life, and shellfish poisonings ... -
Detection of positive selection resulting from Nevirapine treatment in longitudinal HIV-1 reverse transcriptase sequences
(University of the Western Cape, 2006)Nevirapine (NVP) is a cheap anti-retroviral drug used in poor countries worldwide, administered to pregnant women at the onset of labour to inhibit HIV enzyme reverse transcriptase. Viruses which may get transmitted to ... -
Detection of selective tyrosinase inhibitors from some South African plant extracts of lamiaceae family
(University of the Western Cape, 2016)Various dermatological disorders, such as formation of black pigmented patches on the surface of the skin arise from the over-activity of tyrosinase enzyme's degenerative action. This enzyme is further implicated in the ... -
Detection of selective Tyrosinase inhibitors from some South African plant extracts of Lamiaceae family
(University of the Western Cape, 2016)Various dermatological disorders, such as formation of black pigmented patches on the surface of the skin arise from the over-activity of tyrosinase enzyme's degenerative action. This enzyme is further implicated in the ... -
Determinants for the acceptance and use of mobile health applications: Diabetic patients in the Western Cape, South Africa
(University of Western Cape, 2019)The increased pervasiveness of information communication and technology and increasing internet access creates anticipation for how contemporary technologies can address critical developmental problems. Non-communicable ... -
Determinants for the effective provision of public goods by honduran hometown associations in the United States: the Garífuna case
(2006)The study concludes that the existence of HTAs in the USA is explained by the socially enforced institution of the hijos del pueblo (sons of the town) having a duty to help their hometowns, as well as the private benefits ... -
Determinants influencing the oral health of adults in Seychelles
(University of Western Cape, 2021)Oral diseases are a major public health problem in the Seychelles, amidst a contracting budget coupled by a lack of national oral health policy and strategic plan to promote oral health. The oral disease burden is attributed ... -
Determinants of access and utilization of health care facilities among women in South Africa: The case of the Eastern Cape province
(University of the Western Cape, 2022)Access to healthcare is a requirement for human well-being. However, women who seek medical care when needed are still confronted with significant access barriers. This study aimed to identify the factors influencing the ...