Browsing by Title
Now showing items 5911-5930 of 8878
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Novel adamantane derivatives as multifunctional neuroprotective agents
(University of the Western Cape, 2013)The pathology of neurodegenerative disorders involves multiple steps, and it is probably for this reason that targeting one particular step in a multi-step process has only yielded limited results. Nitric oxide (NO) is ... -
Novel adamantane-chloroquinolin conjugates to overcome plasmodium falciparum chloroquine resistance
(University of the Western Cape, 2017)Malaria poses devastating health and socioeconomic outcomes on global health especially among pregnant women and children below the age of 5 in endemic areas. This is exacerbated by Plasmodium falciparum resistance to ... -
Novel aminoquinoline-polycyclic hybrid molecules as potential antimalarial agents
(University of the Western Cape, 2014)Plasmodium falciparum malaria continues to be a worldwide health problem, especially in developing countries in Africa and is responsible for over a million fatalities per annum. Chloroquine (CQ) is low-cost, safe and was ... -
Novel approach of using Hydrogeochemistry, Hydrogeologic and Hydrostratigraphic techniques in evaluating coastal aquifers in Heuningnes catchment, South Africa
(University of the Western Cape, 2019)The increasing population in search for better social and economic development in coastal areas puts groundwater resources under pressure because of the high fresh water demand for domestic and agriculture use. Seawater ... -
Novel aromatic dendritic-co-poly(3-hexylthiophene) composites for photovoltaic cell application
(University of Western Cape, 2021)Fossil fuels are part of fuels that are formed from natural processes and they are called non-renewable sources of energy. These include natural gas, coal and oil. They have been used for decades to produce energy globally. ... -
Novel genomic approaches for the identification of virulence genes and drug targets in pathogenic bacteria
(University of the Western Cape, 2001)While the many completely sequenced genomes of bacterial pathogens contain all the determinants of the host-pathogen interaction, and also every possible drug target and recombinant vaccine candidate, computational tools ... -
Novel genomic biomarkers for pediatric and adult acute myeloid leukemia
(University of the Western Cape, 2023)Acute myeloid leukemia (AML) is a heterogeneous type of blood cancer that affects individuals of all ages. AML patients are categorized into favorable, intermediate, and adverse risks based on patients' genomic features ... -
Novel gold nanoparticles of drought tolerance enabler GYY4137
(University of the Western Cape, 2019)Different nanoparticles have the ability to improve plant tolerance to drought stress. In the study we report for the first time novel morpholin-4-ium 4-methoxyphenyl (morpholino) phosphinodithioate capped- gold nanoparticles ... -
Novel Nanostructure Electrocatalysts for Oxygen Reduction and Hydrogen Evolution Reactions
(University of Western Cape, 2020)widespread use of fossil energy has been most convenient to the world, while they also cause environmental pollution and global warming. Therefore, it is necessary to develop clean and renewable energy sources, among which, ... -
Novel nanostructure electrocatalysts for oxygen reduction and hydrogen evolution reactions
(University of the Western Cape, 2020)The widespread use of fossil energy has been most convenient to the world, while they also cause environmental pollution and global warming. Therefore, it is necessary to develop clean and renewable energy sources, among ... -
Novel Nanostructure Electrocatalysts for Oxygen Reduction and Hydrogen Evolution Reactions
(University of the Western Cape, 2019)The widespread use of fossil energy has been most convenient to the world, while they also cause environmental pollution and global warming. Therefore, it is necessary to develop clean and renewable energy sources, among ... -
Novel norbornane derivatives as potential neuroprotective agents
(University of Western Cape, 2020)Neurodegenerative disorders are characterised by progressive loss of the brain’s physiological functions as a result of gradual degeneration of neurons in the central nervous system. Even though they are classified as ... -
Novel poly(propylene thiophenoimine)-co poly(ethylenedioxythiophene) composites of naphthalene diimide for applications in organic photovoltaic cells
(2013)Solar energy generation arises as a result of direct conversion of sunlight into electricity a by solar cell; which is mainly made up of a semiconducting material incorporated into a system. It is emerging as one of the ... -
Novel tricycloundecane derivatives as potential N-methyl-Daspartate receptor and calcium channel inhibitors for neuroprotection
(University of the Western Cape, 2014)This study focused on the synthesis of a series of novel tricycloundecane derivatives and evaluation of these compounds for neuroprotection using the fluorescent ratiometric calcium assay that indicates the ability of the ... -
Novice occupational therapists’ perceptions and experiences of professional socialisation in the first year of practice in South Africa
(University of the Western Cape, 2018)Professional socialisation is a key dimension within the professional development of an occupational therapy practitioner. Professional socialisation in the first year of practice involves a process of change within the ... -
Novice teachers’ perceptions and experiences of the practical learning module and their preparedness to teach in the foundation phase of schooling
(University of the Western Cape, 2024)This study explored novice teachers’ perceptions and experiences of a Practical Learning Module. It addresses the problem of novice teacher efficacy, working from the premise that teacher quality affects education quality. ... -
De novo assembly of the rooibos genome
(University of Western Cape, 2020)Rooibos (Aspalathus linearis) is endemic to the Cederberg region of South Africa, and one of the few indigenous medicinal plants commercially cultivated in the country. International interest in rooibos is growing, and ... -
Nuclear level densities and gamma-ray strength functions in Ta isotopes and nucleo-synthesis of ¹⁸ᴼTa
(University of the Western Cape, 2016)Most stable and extremely low abundance neutron deficient nuclei with Z ≥ 34 are referred to as p-nuclei. Nearly all p-nuclei with A < 110 are most likely produced in the rp-process while almost all A > 110 are thought ... -
The Nuclear Non-Proliferation Treaty : a comparison of realist, liberal and constructivist views
(University of the Western Cape, 2012)The Nuclear Non-Proliferation Treaty (NPT) was negotiated to stop the proliferation of nuclear weapons, resulting from the dangers associated with the use of these weapons well visible during 1945, in Hiroshima and Nagasaki ... -
Nuclear structure studies in the A=136 region using transfer reactions
(University of the Western Cape, 2018)This thesis describes research work undertaken to study neutron pairing correlations in 136Ba via the 138Ba(p, t) pair transfer reaction and to perform high-precision spectroscopy of low-lying states in 136Cs using the ...