Browsing by Author "Bendou, Hocine"
Now showing items 1-6 of 6
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Baobab LIMS: An open source biobank laboratory information management system for resource-limited settings
Bendou, Hocine (University of the Western Cape, 2019)A laboratory information management system (LIMS) is central to the informatics infrastructure that underlies biobanking activities. To date, a wide range of commercial and open source LIMS are available. The decision ... -
Computational analysis of multi-omic data for the elucidation of molecular mechanisms of neuroblastoma
Giwa, Abdulazeez (University of Western Cape, 2021)Neuroblastoma is the most common extracranial solid tumor in childhood. The survival rates of patients with neuroblastoma, especially those in the high-risk category, are still low despite varied therapies. The detailed ... -
Discovering cancer subtypes by tracking cancer progression with transcriptomic data through the multi-stage process of cancer development.
Livesey, Michelle Chantel (University of the Western Cape, 2023)Background: The development of cancer is driven by genomic alterations, which become more heterogeneous as the disease progresses throughout the stages. Consequently, cancer patients have differential levels of sensitivity ... -
Identification of insertion-induced enhancers linked to gene drivers within non-coding DNA using a pipeline for diffuse large b-cell lymphoma H3K27ac ChIP-seq data
Jassiem, Wardah (University of the Western Cape, 2022)Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma (NHL) and incorporates a diverse range of illnesses with varying biology, clinical manifestations, and therapeutic responses. Functional ... -
Novel genomic biomarkers for pediatric and adult acute myeloid leukemia
Bendou, Hocine; Eshibona, Nasr O M (University of the Western Cape, 2023)Acute myeloid leukemia (AML) is a heterogeneous type of blood cancer that affects individuals of all ages. AML patients are categorized into favorable, intermediate, and adverse risks based on patients' genomic features ... -
Reconstruction of gene regulatory networks of inflammation-associated genes in different clinical stages of diffuse large B-cell lymphoma
Mfuphi, Nomlindelo Witness (University of the Western Cape, 2022)Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous malignancy that is driven by complex gene regulatory networks (GRNs). Numerous genes exert distinct effects on the progression and therapeutic outcome of DLBCL. ...