Browsing Magister Scientiae - MSc (Bioinformatics) by Author "Cloete, Ruben"
Now showing items 1-2 of 2
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Investigating the structural effect of Raltegravir resistance associated mutations on the South African HIV-1 Integrase subtype C protein structure
Chitongo, Rumbidzai (University of the Western Cape, 2020)Background and Aims Human Immunodeficiency Virus (HIV) type 1 group M subtype C (HIV-1C) accounts for nearly half of global HIV-1 infections, with South Africa (SA) being one of the countries with the highest infection ... -
Molecular modeling and simulation studies to prioritize sequence variants identified by whole-exome sequencing in a South African family with Parkinson's disease
Hassan, Maryam (University of Western Cape, 2021)Parkinson’s disease (PD) is a neurodegenerative disorder that occurs due to a loss of dopaminergic neurons in the substantia nigra. It is one of the most common neurodegenerative disorders, ranking second only to Alzheimer’s ...