Browsing Philosophiae Doctor - PhD (Biotechnology) by Issue Date
Now showing items 41-60 of 100
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Manipulating biotic and abiotic factors to enhance the remediation of agri-industrial wastewater in pilot-scale constructed wetlands
(University of the Western Cape, 2012)As a consequence of various cellar activities the wine industry produces copious volumes of potentially hazardous wastewater each year. South Africa is one of the top ten wine-producing countries, making the successful ... -
Modulation of soybean and maize antioxidant activities by Caffeic acid and nitric oxide under salt stress
(University of the Western Cape, 2012)This study explores the roles of exogenously applied nitric oxide, exogenously applied caffeic acid and salt stress on the ontioxidant system in cereal (exemplified by maize) and legume (using soybean as an example) plants ... -
Structural and functional studies of XvPrx2, a type II peroxiredoxin protein from the resurrection plant xerophyta viscosa
(University of the Western Cape, 2012)XvPrx2 is a 1-Cys-containing member of the Prx5 subfamily of peroxiredoxins isolated from the resurrection plant Xerophyta viscosa. It is reported to be up-regulated during periods of desiccation and to protect nucleic ... -
Expression of recombinant S-locus F-box-S2 protein and computational modeling of protein interaction at the self-incompatibility locus of Rosaceae
(2012)Self-incompatibility (SI) is a major mechanism that prevents inbreeding in ow-ering plants, which was identi ed in Rosaceae, Solanaceae and Scrophulariace. In these families, SI is gametophytic and retains inter-speci ... -
Defining the African green monkey (Chlorocebus Aethiops): expression behaviour of selected lipid metabolism genes in response to niacin
(University of Western Cape, 2012)In this century most major medical advances have resulted in part from research on animals and non-human primates such as the African green monkey and therefore often serve as a critical link between basic research and ... -
Modulation of soybean and maize antioxidant activities by caffeic acid and nitric oxide under salt stress
(University of Western Cape, 2012) -
Public participation as governance the role of catchment forums in water governance Mluleki Matiwane
(2012)Catchment forums are concerned groups of people that come together on a voluntary basis in a specific area. They share the same goal and purpose to achieve - sustainable water resources management. These Catchment Forums ... -
Microbial ecology of hot and cold desert edaphic communities
(University of the Western Cape, 2012)This thesis presents significant advances into the microbial ecology of hypolithic communities in two hyperarid deserts. Deserts account for one fifth of the Earths total surface area. These zones differ substantially in ... -
Metagenome sequencing and in silico gene discovery: From genetic potential to function
(University of the Western Cape, 2012)In a previous study, metagenomic DNA extracted from Antarctic Dry Valley soils was used to construct a large contig bacterial shotgun fosmid library (Anderson, 2008). In the current study, clones were selected based on ... -
Development of nanotechnology-based drug delivery and imaging system to the white adipose tissue vasculature using Wistar Rat Model
(University of the Western Cape, 2013)Obesity is a complex metabolic disease of excessive fat accumulation. It is a worldwide epidemic affecting billions of people and its pharmacological management is hampered by drug toxicity and undesirable side effects. ... -
Tumour specific targeted in vitro theranostics application of fabricated nanostructures in a multi-drug resistant ovarian carcinoma cell line
(University of the Western Cape, 2013)Ovarian cancer is called the “Silent Killer” as it is often diagnosed in advanced stages of the disease or misdiagnosed which ends with a poor prognostic outcome for the patient. A high rate of disease relapse, a high ... -
A transcriptome analysis of apple (Malus x domestica Borkh.) cv ‘golden delicious’ fruit during fruit growth and development
(2013)The growth and development of apple (Malus x domestica Borkh.) fruit occurs over a period of about 150 days after anthesis to full ripeness. During this period morphological and physiological changes occur defining fruit ... -
Identification of differentially expressed proteins in obese rats fed different high fat diets using proteomics and bioinformatics approaches
(2013)Obesity is a medical condition in which an energy imbalance leads to excessive accumulation of body fat. Obesity leads to a reduction in life expectancy through its association with chronic diseases of lifestyle. The ... -
Mapping and identification of disease resistance candidate genes in three Malus populations using SSRs, DArT and Infinium SNP markers and Illumina sequencing technology
(University of the Western Cape, 2014)Apple scab, powdery mildew and woolly apple aphid are a major concern for apple breeders and producers. Control of these diseases is a significant economic and marketing priority for the South African apple industry. ... -
Population structure and demographics in Nigerian populations utilizing Y-chromosome markers
(University of the Western Cape, 2014)Nigeria is peopled by ethnically and linguistically diverse populations of which little were known until the last few millennial. The absence of major natural geographical barrier increases the possibility of the populations ... -
A computational framework for transcriptome assembly and annotation in non-model organisms: the case of venturia inaequalis
(University of the Western Cape, 2014)In this dissertation three computational approaches are presented that enable optimization of reference-free transcriptome reconstruction. The first addresses the selection of bona fide reconstructed transcribed fragments ... -
Pharmacogenomics of solute carrier transporter genes in the Xhosa population
(University of the Western Cape, 2014)Solute carrier transporters belonging to the major facilitator family of membrane transporter are increasingly being recognized as a possible mechanism to explain inter-individual variation in drug efficacy and response. ... -
Analysis of the early events in the interaction between Venturia inaequalis and the susceptible Golden Delicious apple (Malus x domestica Borkh.)
(University of the Western Cape, 2014)Apple (Malus x domestica) production in the Western Cape, South Africa, is one of the major contributors to the gross domestic product (GDP) of the region. The production of apples is affected by a number of diseases. One ... -
New genetic tools to engineer starch production in crops
(University of the Western Cape, 2014)Starch is a major carbohydrate reserve in many plants, providing energy during heterotrophic growth and it is contained in large amounts in staple foods such as potatoes, wheat, maize, rice, sorghum and cassava. Apart from ... -
Genomic and proteomic analysis of drought tolerance in Sorghum (Sorghum bicolor (L.) Moench)
(University of the Western Cape, 2014)Drought is the most complex phenomenon that remained to be a potential and historic challenge to human welfare. It affects plant productivity by eliciting perturbations related to a pathway that controls a normal, ...