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Now showing items 11-13 of 13
Novel tricycloundecane derivatives as potential N-methyl-Daspartate receptor and calcium channel inhibitors for neuroprotection
(University of the Western Cape, 2014)
This study focused on the synthesis of a series of novel tricycloundecane derivatives and evaluation of these compounds for neuroprotection using the fluorescent ratiometric calcium assay that indicates the ability of the ...
The impact an accredited third party assessor will have on the regulator’s response time
(University of the Western Cape, 2014)
Globally regulators have been under scrutiny for delays in market application (MA) approvals. The main issue that surfaces in studies related to these delays is a shortage in competent reviewers. The concept of a third ...
Novel aminoquinoline-polycyclic hybrid molecules as potential antimalarial agents
(University of the Western Cape, 2014)
Plasmodium falciparum malaria continues to be a worldwide health problem, especially in developing countries in Africa and is responsible for over a million fatalities per annum. Chloroquine (CQ) is low-cost, safe and was ...