Browsing Magister Pharmaceuticae - MPharm by Title
Now showing items 57-76 of 143
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Evaluation of antihistamines for in vitro antimalarial activity against Plasmodium falciparum
(2010)The declining efficacy of antimalarial drugs against resistant Plasmodium falciparum strains in several endemic regions has amplified the world’s burden of neglected diseases. This has highlighted the need for alternate ... -
Evaluation of guidelines for clinical trials of traditional plant medicines
(University of the Western Cape, 2005)The World Health Organization estimates that 4 billion people use herbal medicine for some aspect of primary health care. These herbal products are however mostly used without the necessary clinical trial done to prove ... -
The evaluation of markers for quality control studies of flavonoid-containing medicinal preparations
(University of the Western Cape, 2004)In spite of the high utilization of South African traditional medicine, the therapeutic potential and the chemical components of many plant preparations are unknown. For the safe and effective use of these medicinal ... -
The evaluation of microwave drying on the polymorphic characteristics of carbamazepine granules prepared by the wet granulation process.
(Univeraity of the Western Cape, 2006)The drying conditions of granules for tabletting prepared by the wet granulation process traditionally involve conduction, convection and radiation heat transfer. Despite various technological advances utilizing combinations ... -
Evaluation of rational use of medicines in public healthcare facilities
(University of the Western Cape, 2020)Access to quality healthcare in South Africa is known to be unequal, with those who can afford it, receiving the best quality healthcare services in the private sector, and those who cannot afford it, having to receive ... -
Evaluation of satherlandia frutescens for anti.cancer activity
(University of the Western Cape, 2002)The claim for anti-cancer activity of the plant Sutherlandiafrutescens was investigated against some cancer cell lines in-vitro and against a dichlorvos induced chemical carcinogenesis in-vivo. A preliminary phytochemical ... -
Evaluation of the anticonvulsant activity of Elytropappus rhinocerotis (L.f) Less
(University of the Western Cape, 2016)M.Pharm thesis, Discipline of Pharmacology, School of Pharmacy, University of the Western Cape. Epilepsy is a worldwide neurological disorder which is also prevalent in South Africa. Herbal medicines, besides orthodox ... -
Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta Graveolens L. in mice and rats
(University of the Western Cape, 2012)Evaluation of the antinociceptive, anti-inflammatory and antipyretic activities of Ruta graveolens L. in mice and rats FIRDOWS LOONAT M. Pharm. Pharmaceutical Sciences thesis: School of Pharmacy, University of the Western ... -
An Evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, Traditional Medicinal Plants used in the Western Cape
(University of the Western Cape, 2002)The overall objective of this study was to investigate the claims that Mentha longifolia (ML) and Artemisia afra (AA) have anti-asthmatic properties. To realize this objective we were to determine the effects that the ... -
An evaluation of the Bronchodilator properties of Mentha longifolia and Artemisia afra, traditional medicinal plants used in the Western Cape.
(University of the Western Cape, 2002)The overall objective of this study was to investigate the claims that Mentha longifulia (ML) and Artemisia afra (AA) have anti-asthmatic properties. To realize this objective we were to determine the effects that the ... -
Evaluation of the pulmonary effects of the traditionally prepared Artemisia afra steam inhalation and nebulized aqueous extract and the possible involvement of flavonoid luteolin
(University of the Western Cape, 2006)Artemisia afra is a popular medicinal plant traditionally used to treat respiratory conditions such as asthma, bronchitis etc., most frequently as a steam inhalation. The effectiveness of this steam inhalation, its active ... -
An evaluation of western herbal complementary medicine labelling in South Africa, to determine whether the product labelling information complies with established herbal monographs and whether it meets local regulatory requirements
(University of the Western Cape, 2015)Medicines (CMs) are widely available to the South African public. However, CMs have not yet been evaluated by the Medicines Control Council (MCC). The MCC has published new guidelines for the regulation of CMs, with which ... -
Examining the inventory management of antiretroviral drugs at community health centres in the cape metropole, Western Cape
(2013)South Africa is faced with a high number of people living with HIV/AIDS, and subsequently a great need to access quality medicines for improving patient therapeutic outcomes. Antiretroviral drugs (ARVs) require rigid, ... -
Exploring a participatory multi-stakeholder engagement approach to address chronic medicine use
(University of the Western Cape, 2023)Background: In South Africa, chronic diseases (CD) fall into the quadruple burdens of diseases. In 2018 the World Health Organization (WHO) reported that chronic diseases were responsible for more than fifty percent of ... -
The formulation and characterisation of corticosteroid loaded Ethosomes for topical delivery
(University of the Western Cape, 2020)Background/Introduction: Atopic dermatitis (AD) is one of the most prevalent diseases worldwide. It is a rapidly growing field of study with several research avenues to explore its pathophysiology and to find innovative ... -
Formulation and evaluation of polymeric micelles for improved oral delivery of tenofovir disoproxil fumarate and zidovudine using poly-lactic-co-glycolic acid nanoparticles
(University of the Western Cape, 2018)Background: Tenofovir disoproxil fumarate (TDF) and Zidovudine (AZT) are both nucleotide and nucleoside analogue reverse transcriptase inhibitors (NtRTIs and NRTIs), respectively. They are used for the management and ... -
The formulation and evaluation of rapid release tablets manufactured from Artemisia Afra plant material
(University of the Western Cape, 2004)Infusions, decoctions, alcoholic preparations and other dosage forms of Artemisia afra are frequently used in South African traditional medicine. Generally when these preparations are made without applying good manufacturing ... -
Formulation and evaluation of tablets manufactured from Dodonaea Angustifolia plant material
(University of the Western Cape, 2001)The liquid dosage form is the most frequently used form for traditional plant medicines. However, this dosage form is associated with many problems, e.g. physicochemical instability, microbial contamination, etc. which may ... -
Formulation and evaluation of zidovudine cyclodextrin inclusion complex to enhance acid lability and palatability
(University of the Western Cape, 2016)Background: Zidovudine (AZT) is a very useful drug for the management of Human Immunodeficiency Virus (HIV) infection. Its optimal use is limited by its bitter taste, sparing solubility (20.1 mg/ml) and acid lability. ... -
Formulation of a nevirapine co-crystal as a liquid dosage form
(University of the Western Cape, 2016)Co-crystals are a solid phase phenomena that could enhance the physicochemical properties of an active pharmaceutical ingredient. A co-crystal has never been incorporated into a liquid dosage form with the assurance of ...