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Proteomic and SNP analysis of the Cadherin 10 type-II (CDH10) gene, in the South African autistic population
(University of the Western Cape, 2013)
Autism or autism spectrum disorder (ASD) is a very diverse neurological disorder that manifests specifically in children and infants between the ages of two to three years of age. An individual suffering is deemed as ...
Bacteriophage diversity in haloalkaline environments
(University of the Western Cape, 2013)
There are limited reports on virus population in haloalkaline environments;
therefore the aim of this study was to investigate the genetic diversity and
biology of bacteriophage communities in these environments. Bacteria ...
Engineering bacterial magnetic nanoparticles
(University of the Western Cape, 2013)
Magnetosomes, produced by magnetotactic bacteria (MTB), are the most attractive alternative source of non-toxic biocompatible magnetic nanoparticles (MNPs). A magnetosome contains Fe2O4 magnetite with properties superior ...
Barley anther culture: determining the optimal pre-treatment for green plant regeneration
(2013)
Doubled Haploid (DH) Technology is an important tool for plant breeding and
biotechnological applications as it accelerates the breeding cycle of plants by shortening the time required to attain homozygosity. Anther culture ...
Investigating the functional interaction of transcription regulator card of mycobacterium tuberculosis with ribonucleic acid polymerase
(2013)
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). TB mainly affects lungs of patients but other parts of the body can also be affected. It kills approximately 2 million people annually. ...
Actinobacterial and archaeal diversity in lake Magadi, Kenya
(University of the Western Cape, 2013)
Microorganisms of the class Actinobacteria and domain Archaea are interesting from a
biotechnological perspective owing to their metabolic attributes as producers of
secondary metabolites and resilience under harsh ...
Targeted delivery of embelin to cancer cells
(University of the Western Cape, 2013)
Apoptosis or programmed cell death is vital to the development of organisms as they
maintain the balance between cell death and cell growth. Failure to activate apoptosis has
been implicated in carcinogenesis and often ...
Evaluating the specancer cell targeting peptides for applications in cancer diagnostics
(University of the Western Cape, 2013)
Cancer is a disease most often associated with poor prognosis. During the development of the
disease, cells acquire genetic mutations which result in changes in bio-molecules (DNA and
protein), thus altering normal ...
Impact of vanadium stress on physiological and biochemical characteristics in heavy metal susceptible and tolerant Brassicaceae
(University of the Western Cape, 2013)
There is an influx in heavy metals into soils and ground water due to activities
such as increased mineral mining, improper watering and the use of heavy metal
contaminated fertilizers. These heavy metals are able to ...
Discriminative eradication of cancer cells using quantum dots functionalised with peptide-directed delivery of a pro-apoptotic peptide
(2013)
The therapeutic goal of cancer treatment is to trigger selective cell death in cancer cells. To eliminate cancerous cells effectively, the anti–cancer drugs must be targeted to the affected cells. However, anti–cancer drugs ...