Magister Scientiae - MSc (Biotechnology): Recent submissions
Now showing items 21-40 of 262
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Prevalence of uncontrolled hypertension and the pharmacogenomics of enalapril-induced adverse effects among patients in the Vhembe district
(University of the Western Cape, 2022)Controlling blood pressure (BP) among individuals with hypertension is important in the prevention of cardiovascular diseases (CVDs). However, maintaining optimal BP levels in individuals who are prone to drug-induced ... -
Ancient Genes in Cancer Gene Expression?
(University of the Western Cape, 2004)Backsround: The Cancer/testis (CT) antigens are a division of germ cell specific genes not expressed in somatic cells, exceptions being placental cells and 20Vo - 4OVo of cancer types. The aptitude of CT antigens to elicit ... -
Exogenous carbon monoxide and jasmonic acid mitigate salt stress in Sorghum bicolor
(University of the Western Cape, 2022)The agricultural sector plays an important role in the world economy. Expanding research is piloting its improved contribution to the economic sector. Despite the economic gain, the increasing population has already put ... -
The effect of chitosan in the germination and growth of sorghum bicolor under salt stress
(University of the Western Cape, 2022)The agricultural sector has been facing enormous challenges including reduced crop yield and increased food production demand to cater for the growing population. Crop production is severely affected by abiotic and biotic ... -
In vitro evaluation of Leonotis leonurus to validate its potential as an alternative anti-diabetic drug
(University of the Western Cape, 2022)Africa is a rich source of medicinal plants with South Africa being known as a country with a strong history of traditional healing, which masses a variety of approximately 30 000 flowering plants and accounting for ... -
Biocontrol potential of fungal endophytes against Fusarium proliferatum in maize
(University of the Western Cape, 2022)Fusarium proliferatum is a fungal pathogen that is the cause of numerous diseases in various crops of fruit and vegetables. About 25% of the maize crops harvested annually are affected by mycotoxins produced by F. ... -
Influence of a selected endophyte consortium on salinity responses in Medicago sativa
(University of Western Cape, 2022)Salinity is one of the major limiting factors to crop production, which consequently contributes to the risk of reduced food security. Among other factors, food security depends on availability of sufficient and nutritious ... -
DNA metabarcoding for the identification of species within vegetarian food samples
(University of the Western Cape, 2021)Aims DNA metabarcoding has recently emerged as a valuable supplementary tool to ensure food authenticity within the global food market. However, it is widely known that highly processed food samples are one of DNA ... -
Comparison of multi-gene integration strategies in CRISPR-based transformation of Saccharomyces cerevisiae
(University of the Western Cape, 2021)Saccharomyces cerevisiae is an important host in industrial biotechnology. This yeast is the host of choice for the first and second-generation biofuels for ethanol production. Genome modification in S. cerevisiae has been ... -
Screening of marine bacteria as a source of bioactive secondary metabolites
(University of Western Cape, 2021)Marine invertebrate associated (MIA) bacteria are an important source of bioactive secondary metabolites with the potential to address the current anti-microbial resistance crisis experienced globally. Secondary metabolites ... -
Comparison of multi-gene integration strategies in CRISPR-based transformation of Saccharomyces cerevisiae
(University of Western Cape, 2021)Saccharomyces cerevisiae is an important host in industrial biotechnology. This yeast is the host of choice for the first and second-generation biofuels for ethanol production. Genome modification in S. cerevisiae has been ... -
Analysis of ammonia-oxidizing bacteria associated with the roots of Proteaceae plant species in soils of Fynbos ecosystem
(University of the Western Cape, 2005)Molecular methods were used to investigate the microbial diversity and community structure of ammonia-oxidizing bacteria (AOB) associated with the roots of the Proteaceae plant family. The identification of ammonia ... -
Microbiology of fly ash-acid mine drainage co-disposal processes
(University of the Western Cape, 2005)The waste products acid mine drainage (AMD), formed during coal mining and fly ash (FA) from coal burning power generation, pose substantial environmental and economic problems for South Africa. Eskom has developed a ... -
Recombinant expression of the pRb- and p53-interacting domains from the human RBBP6 protein for in vitro binding studies
(University of the Western Cape, 2004)This thesis describes the cloning and recombinant expression of domains from the human RBBP6 protein for future in vitro binding studies with pRb and p53. RBBP6 is a splicing-associated protein that is known to interact ... -
Structural characterisation of the interaction between RBBP6 and the multifunctional protein YB-l
(University of the Western Cape, 2010)Retinoblastoma binding protein 6 (RBBP6) is a 250 kDa RING finger-containing protein whose function is known to be mediated through interaction with other proteins. RBBP6 plays a role in the regulation of the tumour ... -
Laccases from actinomycetes for lignocellulose degradation
(University of the Western Cape, 2012)Lignocellulose has a complex structure composed mainly of lignin, hemicellulose and cellulose. Several enzymes are needed for the degradation of lignocellulose into simple sugars. Actinomycetes are known to produce laecases ... -
Identification and validation of putative therapeutic and diagnostic antimicrobial peptides against HIV: An in silico approach
(University of the Western Cape, 2013)Background: Despite the effort of scientific research on HIV therapies and to reduce the rate of HIV infection, AIDS still remains one of the major causes of death in the world and mostly in Sub-Saharan Africa. To date, ... -
The impact of different storage temperatures and storage period on the antioxidant activity of pomegranate
(University of Western Cape, 2021)Fruit storage at cold temperatures is normally used to delay decay while maintaining the fruit’s quality. However, storage at low temperatures for a prolonged period causes some important metabolic functions within the ... -
Effects of nitric oxide and hydrogen peroxide on antioxidant enzyme activity in zea mays subjected to drought
(University of Western Cape, 2021)Agricultural practices are significantly affected by drought. Drought is one of the most important plant stresses, causing several physiological, morphological, biochemical, and molecular changes in plants. Drought stress ... -
Improvement of cell-surface adhered cellulase activities in recombinant strains of Saccharomyces cerevisiae engineered for consolidated bioprocessing
(University of Western Cape, 2021)Consolidated bioprocessing (CBP), in which a single organism in a single reactor is responsible for the conversion of pretreated lignocellulosic biomass to bioethanol, remains an attractive option for production of commodity ...