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Stigmatization of and discrimination against people who are HIV positive, or have AIDS – a female perspective in Zwartwater, Eastern Cape Province
(University of the Western Cape, 2011)
The aim of this study is to investigate the perceived stigmatization of and
discrimination against people who are HIV positive or people who are living with
AIDS. One questionnaire was used to collect qualitative and ...
Construction and analysis of efficient numerical methods to solve mathematical models of TB and HIV co-infection
(University of the Western Cape, 2011)
The global impact of the converging dual epidemics of tuberculosis (TB) and human immunodeficiency virus (HIV) is one of the major public health challenges of our time, because in many countries, human immunodeficiency ...
Formulation and evaluation of polymeric micelles for improved oral delivery of tenofovir disoproxil fumarate and zidovudine using poly-lactic-co-glycolic acid nanoparticles
(University of the Western Cape, 2018)
Background: Tenofovir disoproxil fumarate (TDF) and Zidovudine (AZT) are both nucleotide and nucleoside analogue reverse transcriptase inhibitors (NtRTIs and NRTIs), respectively. They are used for the management and ...
Analysis and implementation of robust numerical methods to solve mathematical models of HIV and Malaria co-infection
(University of the Western Cape, 2011)
There is a growing interest in the dynamics of the co-infection of these two diseases. In this thesis, firstly we focus on studying the effect of a distributed delay representing the incubation period for the malaria ...
Investigating the structural effect of Raltegravir resistance associated mutations on the South African HIV-1 Integrase subtype C protein structure
(University of the Western Cape, 2020)
Background and Aims Human Immunodeficiency Virus (HIV) type 1 group M subtype C (HIV-1C) accounts for nearly half of global HIV-1 infections, with South Africa (SA) being one of the countries with the highest infection ...
Identification and validation of putative therapeutic and diagnostic antimicrobial peptides against HIV: An in silico approach
(University of the Western Cape, 2013)
Background: Despite the effort of scientific research on HIV therapies and to reduce the rate of HIV infection, AIDS still remains one of the major causes of death in the world and mostly in Sub-Saharan Africa. To date, ...
The Synthesis of Biaxial Naphthoquinones and an Initial Investigation regarding their Potential as anti- Mycobacterium tuberculosis and Apoptotic Agents
(University of the Western Cape, 2009)
Tuberculosis and cancer are amongst the most devastating diseases affecting the world today, especially Africa and other less developed countries. Both diseases have the ability to develop resistance against drugs being ...
Stigmatization of and discrimination against people who are HIV positive, or have AIDS - a female perspective in Zwartwater, Eastern Cape Province
(University of the Western Cape, 2011)
The aim of this study is to investigate the perceived stigmatization of and discrimination against people who are HIV positive or people who are living with AIDS. One questionnaire was used to collect qualitative and ...
Management and analysis of HIV -1 ultra-deep sequence data
(University of the Western Cape, 2014)
The continued success of antiretroviral programmes in the treatment of HIV is dependent on access to a cost-effective HIV drug resistance test (HIV-DRT). HIVDRT involves sequencing a fragment of the HIV genome and ...