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Development of nanotechnology-based drug delivery and imaging system to the white adipose tissue vasculature using Wistar Rat Model
(University of the Western Cape, 2013)
Obesity is a complex metabolic disease of excessive fat accumulation. It is a worldwide epidemic affecting billions of people and its pharmacological management is hampered by drug toxicity and undesirable side effects. ...
Zirconium-induced physiological and biochemical responses in two genotypes of Brassica napus L.
(University of the Western Cape, 2015)
South Africa is one of two countries responsible for the production of approximately
80% of the world’s Zr. The increase in mining activity has detrimental effects on the
environment, especially crop plants, as more ...
Discriminative eradication of cancer cells using quantum dots functionalised with peptide-directed delivery of a pro-apoptotic peptide
(2013)
The therapeutic goal of cancer treatment is to trigger selective cell death in cancer cells. To eliminate cancerous cells effectively, the anti–cancer drugs must be targeted to the affected cells. However, anti–cancer drugs ...
Catalyst Coated Membranes (CCMs) for polymerelectrolyte Membrane (PEM) fuel cells
(University of the Western Cape, 2010)
The main objective of this work it to produce membrane electrode assemblies (MEAs) that have improved performance over MEAs produced by the conventional manner, by producing highly efficient, electroactive, uniform catalyst ...
Development of nanotechnology-based therapeutic approaches to treat HIV
(University of the Western Cape, 2012)
The rapidly expanding field of nanotechnology has been the focus of many biologists with regard to drug delivery. The ability of nanoparticles to enter cellular compartments makes it possible to explore specific treatment ...
Characterization of platinum-group metal nanophase electrocatalysts employed in the direct methanol fuel cell and solid-polymer electrolyte electrolyser
(University of the Western Cape, 2005)
Characterization of nanophase electrocatalysts, which are an essential part in the direct methanol fuel cell (DMFC) and solid-polymer electrolyte (SPE) electrolyser, have been studied in this work. Their nanoparticulate ...
Preparation and physico-chemical properties of nickel nanostructured materials deposited in etched ion-track membrane
(University of the Western Cape, 2005)
The development of finely dispersed powders and superfine-grained materials intended for application in various areas of science and engineering is one of the challenges facing modern nanotechnology. Thus, specific fundamental ...
The development of nanotechnology-based detection systems for the diagnosis of breast cancer
(University of the Western Cape, 2015)
Breast cancer is one of the major causes of death in South Africa. About 1 in 29 South African women are at risk of developing this type of cancer in their lifetime. The global incidence of breast cancer also increases ...
The interaction between 6 MV X-rays and p(66)/Be neutrons with spherical gold nanoparticles to induce cellular damage
(University of the Western Cape, 2016)
Despite the advances in therapies such as chemotherapy and radiotherapy, tumours have been shown to be resistant to the treatments. Gold nanoparticles (AuNPs) have been recognized as effective radiosensitizers of low energy ...
Synthesis and characterization of cathode catalysts for use in direct methanol fuels cells
(University of the Western Cape, 2010)
In this work a modified polyol method was developed to synthesize in-house
catalysts. The method was modified for maximum delivery of product and proved to be quick and efficient as well as cost effective. The series of ...