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Comparison of the physicochemical characteristics and flavonoid release profiles of Sutherlandia frutescens phytosomes versus liposomes
(University of the Western Cape, 2016)
Sutherlandia frutescens is a traditional plant medicine widely used in South Africa. Traditionally, the leaves of S. frutescens are mainly used as a tea, but these traditional dosage forms have several disadvantages, ...
Content levels, in vitro dissolution and predicted bioavailability of flavonoids from Sutherlandia frutescens leaf powder and aqueous extracts
(University of the Western Cape, 2015)
Various formulations of the popular South African medicinal plant, Sutherlandia frutescens,are commercially available, with no documented specifications for quality assessment. With plans already underway for a clinical ...
Effects of environmental growth conditions on the levels of sutherlandins 3 and 4 and sutherlandiosides B and D, in Sutherlandia frutescens (L.) R. Br.
(University of the Western Cape, 2011)
Sutherlandia frutescens (L.) R. Br. (Fabaceae), indigenous to the Western Cape region of South Africa, is found in a Mediterranean-type climate known for its many environmental stressors that can influence the levels of ...
Investigation of the in vitro bioavailability of luteolin from modified preparations of Artemisia afra
(University of the Western Cape, 2014)
Artemisia afra (A. afra) is traditionally used for a variety of ailments and contain flavonoids e.g. luteolin which may contribute to some of its activity. It is generally administered as a tea or decoction, and such liquid ...
The effect of flavonoids on the in vitro activity of antibiotics against Staphylococcus aureus
(University of the Western Cape, 2012)
Staphylococcus aureus is a Gram-positive coccus belonging to the Stapylococcaeae family. S. aureus causes a wide range of infections that range from skin infections to lifethreatening infections such as pneumonia and ...
Gene expression of xenobiotic metabolising enzymes in rat liver and kidney: differential effects of rooibos and honeybush herbal teas
(2011)
Laboratory studies, epidemiological investigations and human clinical trials indicate
that flavonoids have important effects on cancer chemoprevention and therapy.
Flavonoids may interfere in several steps that lead to ...
The synthesis and electrochemical studies of chalcones and flavanones: an investigation of their antioxidant activity
(University of Western Cape, 2013)
Flavonoids, one of the biggest classes of secondary metabolites, are found abundantly in
nature in a broad range of fruits, vegetables and beverages such as tea, coffee, beer, wine and fruit drinks. Flavonoids have been ...
The impact of storage time and seasonal harvesting on biomarker levels of lessertia frutescens
(University of Western Cape, 2012)
In South Africa, it is estimated that approximately 70% of the population frequently make use of traditional medicinal plants for their health care needs. The use of Lessertia frutescens by the various cultural groups in ...
Use of antioxidant activity and flavonoid levels to assess the quality of commercially available solid dose Sutherlandia frutescens products
(University of the Western Cape, 2010)
The overall aims of this project were to assess the pharmaceutical quality and consistency of commercially available solid dose Sutherlandia frutescens containing products (viz. tablets & capsules) by exploring the use of ...
Aspects of the gastrointestinal uptake and metabolism of luteolin derivatives from Artemisia afra aqueous extract (preclinical)
(University of the Western Cape, 2011)
The aim of this study was to investigate the effect the plant matrix and the structure of the flavonoid (i.e. whether aglycone or glycoside) may have on the gastrointestinal uptake and metabolism of luteolin derivatives ...