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Aptamer selection against GFRa1 for its application in the prognosis of breast cancer
(University of the Western Cape, 2019)
Breast cancer is the second most common cancer amongst South African women. Despite
ongoing efforts to combat breast cancer, current prognostic and/or therapeutic monitoring
methods are limited since very little improvement, ...
Proteomic and SNP analysis of the Cadherin 10 type-II (CDH10) gene, in the South African autistic population
(University of the Western Cape, 2013)
Autism or autism spectrum disorder (ASD) is a very diverse neurological disorder that manifests specifically in children and infants between the ages of two to three years of age. An individual suffering is deemed as ...
In silico and molecular validation of identified putative genes and functional analysis of a N K G2D ligand as a breast cancer biomarkers
(University of the Western Cape, 2015)
The current diagnostic, prognostic, predictive and therapeutic monitoring methods
used for breast cancer are limited. Thus, research into more specific, sensitive and
effective strategies is required. Breast cancer is ...
Identification of microRNAs as a class of biomarkers for the early diagnosis of prostate cancer : an in silico and molecular approach
(University of the Western Cape, 2015)
Prostate cancer (PCa) is the second most common form of cancer in men around
the world. In many parts of Africa, data on prostate cancer is sparse. This is
attributed to poor access to testing and diagnostics. The ...
The development of nanotechnology-based detection systems for the diagnosis of breast cancer
(University of the Western Cape, 2015)
Breast cancer is one of the major causes of death in South Africa. About 1 in 29 South African women are at risk of developing this type of cancer in their lifetime. The global incidence of breast cancer also increases ...
The development of graphene oxide sheet- and polyanilino-immunosensor systems for lipoarabinomannan (LAM) tuberculosis biomarker
(University of the Western Cape, 2017)
Tuberculosis (TB) is an infectious disease with adverse effect on a global scale. The disease is one of the major causes of death in sub-Saharan Africa. Nearly 70% of TB-infected persons are co-infected by the human ...
Quantum dots genosensor for Her2/Neu oncogene - a breast cancer biomarker
(University of the Western Cape, 2014)
The human epidermal growth factor receptor (HER)-family of receptor tyrosine kinases; human epidermal growth factor receptor 1, human epidermal growth factor receptor 2, human epidermal growth factor receptor 3 and human ...
Potamanautes warreni biomarker assays to monitor silver nanomaterial contaminants in aquatic environments
(University of the Western Cape, 2016)
There has been extensive growth in nanoscale technology in the last few decades to such a degree that nanomaterials (NMs) have become a constituent in a wide range of manufactured commercial and domestic products. This ...
Identification of biomarkers associated with cervical cancer: a combined in silico and molecular approach
(University of the Western Cape, 2014)
Cervical cancer is the leading cause of cancer mortality among black women in South Africa. It is estimated that this disease kills approximately 8 women in South Africa every day. Cervical cancer is caused by the human ...
The impact of storage time and seasonal harvesting on biomarker levels of lessertia frutescens
(University of Western Cape, 2012)
In South Africa, it is estimated that approximately 70% of the population frequently make use of traditional medicinal plants for their health care needs. The use of Lessertia frutescens by the various cultural groups in ...