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Effects of Fucoidan and Chemotherapeutic agent combinations on Malignant and Non-Malignant breast cell lines
(University of the Western Cape, 2017)
Breast cancer is currently one of the most common malignancies in women. Fucoidan (FUC)
is a natural polysaccharide with anticancer properties. Despite a number of in vitro and in vivo
studies reporting the efficacy of ...
Geochemistry of Gold One tailings and associated contaminant transport into the Randfontein area, Witwatersrand Basin.
(University of the Western Cape, 2017)
The city of Randfontein, in the Witwatersrand, hosts several slimes and tailings storage facilities
which pose potential threat to the environment in the form of acid mine drainage (AMD). The
latter, readily scavenges toxic ...
Identification of coding variants associated with familial systemic lupus erythematosus through whole exome sequencing
(University of the Western Cape, 2016)
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease
characterized by the production of a wide range of autoantibodies directed against selfantigens.
SLE can influence almost any organ system and ...
Detecting Galaxies in the Epoch of Reionization
(University of the Western Cape, 2017)
The aim of this project was to develop a technique that allows us to measure the redshift
of radio galaxies in the Epoch of Reionization. We achieved this by constructing
a parameterization of the 21-cm absorption feature ...
The Generation of Antibodies against Human Coronavirus NL63 (HCoV-NL63) Nucleocapsid Protein
(University of the Western Cape, 2017)
Coronaviruses (CoVs) are enveloped viruses composed of single-stranded, positive sense
RNA viruses with the largest viral genomes among RNA viruses (27-33 kb). In 2004,
human coronavirus NL63 (HCoV-NL63) was discovered by ...
Evaluation of the effect of polyethylene glycol incorporation on the performance of poly(lactic-co-glycolic acid) nanoparticles
(University of the Western Cape, 2016)
Nanoparticle drug delivery is challenged by the binding of proteins in
blood which result in their rapid removal from the circulatory system. Nanoparticles
engineered to delay protein binding have shown to have extended ...
Association between antioxidant activities and drought responses of two contrasting sugar beet genotypes
(University of the Western Cape, 2017)
Sugar beet (Beta vulgaris L), which belongs to the Amaranthaceae family is a biennial crop
widely used as a source of domestic sugar in the European countries, United States, China
and Japan. However, in South Africa, sugar ...
Microbiological parameters that influence the treatment outcomes of monodrug and multidrug-resistant tuberculosis
(University of the Western Cape, 2017)
Previous studies have reported microbiological parameters such as HIV infection, resistance to
anti-TB drugs such as fluoroquinolones, resistance to previous treatment with anti-TB drugsand
extrapulmonary TB, causing poor ...
Geochemical, Sedimentological and Mineralogical Study of Sediments along Coastal Areas of Abu Dhabi, United Arab Emirates (UAE): Implications for Provenance, Depositional Environment, Heavy Minerals and Radiogenic Elements Contamination
(University of the Western Cape, 2017)
This study describes sedimentological, geochemical and mineralogical results of
the beach sediments of Abu Dhabi in the United Arab Emirates in order to understand
the provenance, depositional environment and the level of ...
Investigation of Guayule's Agronomic Performance and Agro-processing in South Africa
(University of the Western Cape, 2017)
Guayule (Parthenium argentatum) is grown for its high quality hypoallergenic natural rubber
latex production. The plant is native to the Chihuahua desert of North America and successful
trials have been done in Europe, the ...