Department of Medical BioSciences
Browse by
Collections in this community
Recent Submissions
-
The effects of green tea, green rooibos and their major flavonoids (EGCG and aspalathin) on testicular cell health in vitro
(University of Western Cape, 2021)The testes play a central role in the male reproductive system, as they represent the sites of male sex steroidogenesis and of spermatogenesis. Leydig cells, located at the testicular interstitium, produce predominantly ... -
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in sh-sy5y cells.
(University of Western Cape, 2021)Parkinson's disease (PD), the second most common neurodegenerative disorder after Alzheimer's disease, is one of the leading disability disorders with about 10 million people affected worldwide. The pathological hallmarks ... -
Identification and validation of putative therapeutic and diagnostic antimicrobial peptides against HIV: An in silico approach
(University of the Western Cape, 2013)Background: Despite the effort of scientific research on HIV therapies and to reduce the rate of HIV infection, AIDS remains one of the major causes of death in the world and mostly in sub-Saharan Africa. To date, neither ... -
Epidemiological study of Tuberculosis in Macassar camp
(University of the Western Cape, 1995)The aim of this study was to determine and evaluate the prevalence of TB infection, active TB cases and the risk factors associated with TB infection in Macassar Camp in Macassar (about 40 km from Cape Town on the False ... -
The effects of silver nanoparticles on the expression of protein biomarkers of cell stress, apoptosis and inflammation by the human liver cancer cell line, HepG2
(University of Western Cape, 2021)Nanoscience is the study of phenomena and objects at the nanoscale (around 1-100 nm), socalled nanomaterials. These nanomaterials exhibit novel properties that are often very different to those of the bulk materials used ... -
The effects of titanium oxide nanoparticles on cultured cells and the immune system
(University of Western Cape, 2021)Engineered nanomaterials derived from various bulk materials are being developed in ever larger quantities and with very diverse chemical compositions. The physical and chemical properties of the smaller nanoparticles are ... -
Investigations on the antifungal and cancer modulating properties of extracts from selected species of Tulbaghia
(University of the Western Cape, 2012)Fusarium verticil/ioides (Sacc) Nirenberg a common phytopathogen of maize and maize-based products produces fumonisin B (FB) mycotoxins that have been related to several diseases such as equine leukoencephalomalacia (ELEM), ... -
The characterisation of human coronavirus nl63 proteins
(University of Western Cape, 2021)Human Coronavirus NL63 (HCoV-NL63) is one of seven coronaviruses (CoVs) that cause respiratory disease in the global population. The Membrane (M) and Nucleocapsid (N) proteins are part of the core CoV-structural proteins, ... -
Comparison between chemical and tissue culture methods to monitor environmental Estrogens
(University of the Western Cape, 2012)Endocrine disrupting compounds (EDCs) are exogenous compounds/chemicals in the environment that interfere with the synthesis, secretion, distribution and function or elimination of natural hormones in the body. Environmental ... -
A quantitative and qualitative assessment of dental aerosols within a dental clinical unit: An avenue for the transmission of resistant nosocomial infection.
(University of Western Cape, 2020)Introduction: Nosocomial infections are infections that occur 48 hours after receiving care for an unrelated condition in a clinic or a hospital environment, many of which are resistant to at least one of the drugs most ... -
Paediatric non-alcoholic fatty pancreas disease and aortic intimal medial thickness: A study identifying potential fatty infiltration of the pancreas and its association with aortic IMT in children exposed to teratogens during pregnancy
(University of the Western Cape, 2020)The incidence of non-communicable diseases is increasing worldwide, with South Africa being no exception. Non-communicable diseases are classified as non-infectious and are often referred to as lifestyle diseases as they ... -
Cell culture biomarkers for monitoring of wastewater pollutants
(University of the Western Cape, 2021)Wastewater is normally composed of a mixture of pollutants. The type and composition of pollutants in a particular wastewater depend on the source of origin. The source and characteristics of a particular wastewater determine ... -
Red palm oil as a therapeutic agent in triple-negative breast cancer patients
(University of the Western Cape, 2020)Purpose: Breast cancer is one of the most frequent and fatal diseases women all around the globe are challenged with today. In women, breast cancer has the highest mortality rate of all cancers and the incidence rate is ... -
CIMT and cardiovascular risk in five-year-old children in a low socioeconomic population exposed to alcohol and nicotine during pregnancy: a case-control study
(University of the Western Cape, 2020)Cardiovascular diseases (CVD) are among the top 10 causes of death in all ages in South Africa. The prevalence of maternal smoking and alcohol consumption during pregnancy is alarmingly high in South Africa. In utero ... -
Transient transgene expression of human coronavirus nl63 orf3 protein
(University of the Western Cape, 2020)Insect-derived baculoviruses have been used extensively as a safe and versatile research model for transgenic protein expression. Preclinical studies have revealed the promising potential of Baculoviruses as a delivery ... -
The role of c-reactive protein as a marker for preterm delivery
(University of Western Cape, 2020)Pregnancy associated maternal morbidity and mortality along with adverse pregnancy outcomes have gained momentum over the past few years, particularly in Sub-Saharan Africa and Southern Asia despite the advances in medical ... -
Transient transgene expression of human Coronavirus nl63 orf3 protein in a baculovirus system
(University of Western Cape, 2020)Insect-derived baculoviruses have been used extensively as a safe and versatile research model for transgenic protein expression. Preclinical studies have revealed the promising potential of Baculoviruses as a delivery ... -
Radiation-induced leukaemia in South Africa: response of lymphocytes and cd34+ cells to different radiation qualities.
(University of the Western Cape, 2020)Epidemiological studies have highlighted that leukaemia can be considered as the most prominent malignancy after radiation exposure during childhood. The lifetime risk on radiation-induced leukaemia for a given dose is 3 ... -
Radiation-induced Leukaemia in South Africa: Response of lymphocytes and cd34+ cells to different radiation qualities
(University of the Western Cape, 2020)Epidemiological studies have highlighted that leukaemia can be considered as the most prominent malignancy after radiation exposure during childhood. The lifetime risk on radiation-induced leukaemia for a given dose is 3 ... -
A baseline evaluation of the cytotoxicity of gold nanoparticles in different types of mammalian cells for future radiosensitization studies
(University of the Western Cape, 2020)Recently nanoparticles (NPs) have been introduced and used in combination with therapeutic approaches to develop nanotechnology-enabled medicine. These nanostructures allow for the exploitation of the physiochemical ...
RSS 1.0