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Now showing items 4629-4648 of 9072
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An in vitro assessment of the bacterial sealing capacity of narrow diameter implants with Morse-taper abutment connections
(University of Western Cape, 2020)Background: Lack of appropriate bone thickness is a common clinical limitation for tooth replacement, often requiring narrow implants, which have shown better results when combined with Morse taper connections. Little is ... -
An in vitro assessment of the bacterial sealing capacity of narrow diameter implants with Morse-taper abutment connections.
(University of Western Cape, 2020)Lack of appropriate bone thickness is a common clinical limitation for tooth replacement, often requiring narrow implants, which have shown better results when combined with Morse taper connections. Little is known about ... -
The in vitro detection and measurement of the unfolded protein response in Saccharomyces cerevisiae
(University of the Western Cape, 2018)Bioethanol is currently the most widely used biofuel and can be used as a direct replacement for current fossil fuel based transportation fuels. Consolidated bioprocessing (CBP), in which bioethanol is produced in a single ... -
The in vitro effect of a tooth bleaching agent on coffee and wine stained teeth
(University of the Western Cape, 2008)Summary: Aim: The aim of this laboratory study is to assess the efficacy of a tooth bleaching agent by evaluating the degree of color change with the use of a spectrophotometer and not by the usual subjective, visual ... -
The in vitro effects of nicotine and selected antibiotics, tunicamycin and thapsigargin on human Breast carcinoma (mcf-7) cells.
(University of the Western Cape, 2012)Cancer is defined as the abnormal growth of genetically mutated or perturbant cells. Nicotine is a known cancer promoter and an apoptotic suppressor. This alkaloid acts on the nicotinic acetylcholine receptors which affects ... -
The in vitro effects of pure and street methamphetamine on the proliferation and cell cycle of mouse brain endothelial (bend5) cells
(2012)The blood-brain barrier (BBB) is an interface between the brain parenchyma and the circulating system. This barrier plays a vital role in protecting the CNS by restricting free paracellular diffusion of molecules from the ... -
In vitro effects of rooibos herbal tea (Aspalathus linearis) against methamphetamine on the mouse blood brain barrier
(University of the Western Cape, 2014)Methamphetamine (MA), also known as ‘Tik’, has detrimental short- and long-term psychological and morphological effects on the central nervous system (CNS). The lipophilic nature of MA allows it to cross the blood-brain ... -
In vitro evaluation of Leonotis leonurus to validate its potential as an alternative anti-diabetic drug
(University of the Western Cape, 2022)Africa is a rich source of medicinal plants with South Africa being known as a country with a strong history of traditional healing, which masses a variety of approximately 30 000 flowering plants and accounting for ... -
In vitro investigation of putative interactions between the RING finger domain of Retinoblastoma Binding Protein 6 (RBBP6) and various substrates
(University of the Western Cape, 2015)Retinoblastoma Binding Protein 6 (RBBP6) is a RING finger-containing protein which plays a critical role in the 3'-end processing of mRNA transcripts. It is a constituent of the human pre-mRNA processing complex but also ... -
An in vitro investigation of the effects of camellia sinensis and aspalathus linearis on benign (RPWE 1) and malignant (LNCaP) prostate cell lines
(University of the Western Cape, 2015)The prostate is prone to three pathological processes that include inflammation, benign prostate hyperplasia (BPH) and tumors. According to the center for Disease and Control 1999-2012 report, prostate cancer is the second ... -
In vitro investigation of the ubiquitination and degradation of p53 by Murine Double Minute 2 (MDM2) and Retinoblastoma Binding Protein 6 (RBBP6)
(University of the Western Cape, 2015)P53 is one of the most important tumour suppressor proteins in the body which protects the cell against the tumourigenic effects of DNA damage by initiating processes such as apoptosis, senescence and cell cycle arrest. ... -
In vitro modulatory effects of fermented rooibos extract (Aspalathus linearis) against ethanol-induced effects on the mouse blood-brain barrier
(University of the Western Cape, 2014)Alcohol abuse is a growing crisis within South Africa, with severe health and socio-economic implications. Alcohol compromises the function of the blood-brain barrier (BBB), and thus its ability to regulate the homeostatic ... -
In vitro neuroprotective effects of boophone disticha, brunsvigia bosmaniae and strumaria truncata extracts in sh-sy5y cells.
(University of Western Cape, 2021)Parkinson's disease (PD), the second most common neurodegenerative disorder after Alzheimer's disease, is one of the leading disability disorders with about 10 million people affected worldwide. The pathological hallmarks ... -
In vitro neuroprotective potential of phyllanthin in MPP+- induced toxicity in SH-SY5Y neuroblastoma cells
(University of the Western Cape, 2023)Parkinson’s disease (PD) is the second most common age-related neurodegenerative disease after Alzheimer’s disease, with an estimated 9 million people projected to be affected worldwide by the year 2030. PD is associated ... -
An In vitro Study of Bacterial Leakage of a Novel Implant Abutment Interface
(University of the Western Cape, 2020)Background: The two-stage implant system has proven to be a successful technique in replacing missing teeth (Nascimento et al., 2008). Nevertheless, the presence of micro-gaps that could entrap microbes at the implant-abutment ... -
An in vitro study of composite repair
(2007)The aim of this study is to investigate the repair bond strength of composite resin following micromechanical and chemical means of retention in improving the repair of composite resin specimens. -
An in vitro study of microleakage and surface microhardness of nanocomposite restorative materials
(University of the Western Cape, 2005)The demand for posterior aesthetic restorations has dramatically increased in recent years. Several new materials have been developed with improved aesthetic, adhesive and mechanical properties. However, microleakage ... -
An in vitro study of post-restorative bleaching: effect on microleakage
(University of the Western Cape, 2010)Aim and Objectives: To assess the effect of bleaching on the marginal integrity of Class V composite resin restorations. To determine the effect of a 6% hydrogen peroxide over the counter and a 38% hydrogen peroxide in-office ... -
An in vitro study of the microleakage of a compomer (polyacid modified resin composite) bonded to enamel and dentine with different bonding systems and the effect of saliva contamination there of.
(Stellenbosch University, 2002)Restorative systems classified as polyacid modified composite resins, or compomers, have appeared on the market. An example of this is Dyract AP. Dyract AP must be used with the Prime & Bond NT bonding system. Prime & ... -
An in vitro study of the properties of GICs with bioactive biomaterial modification
(University of the Western Cape, 2019)The fluoride release and chemical adherence to tooth structure remain the most desirable features of glass ionomer restorative cements (GICs). Although the physical properties for multi-surface restorations are well-defined, ...