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Predictors of death among tuberculosis patients while on treatment in local health facilities in Francistown
(University of the Western Cape, 2016)
Background: Botswana has one of the highest TB incidence rates in the world. Tuberculosis in those without HIV infection accounts for 13% of adult mortality and in those living with TB and HIV in Botswana account for 40% ...
Formulation and evaluation of zidovudine cyclodextrin inclusion complex to enhance acid lability and palatability
(University of the Western Cape, 2016)
Background: Zidovudine (AZT) is a very useful drug for the management of Human
Immunodeficiency Virus (HIV) infection. Its optimal use is limited by its bitter taste, sparing solubility (20.1 mg/ml) and acid lability. ...
In-silico optimization and molecular validation of putative anti-HIV antimicrobial peptides for therapeutic purpose
(University of the Western cape, 2016)
AIDS is considered a pandemic causing millions of deaths worldwide and a cure for this disease is still not available. Failure to implement early treatments due to the poor diagnostic
methods and ineffective therapeutic ...
An investigation of the knowledge and skills of health care providers on early infant diagnosis of HIV in Mzuzu, Malawi
(University of the Western Cape, 2016)
Early infant diagnosis (EID) programmes offer diagnosis of HIV, which facilitates provision of life-saving care to infants infected with HIV. Implementing programmes for EID and treatment has proved challenging in Malawi. ...