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Ursolic acid and oleanolic acid as novel therapeutic agents in breast cancer
(University of the Western Cape, 2015)
Breast cancer is one of the most common cancers among women in South Africa and the second leading cause of cancer death after lung cancer. According to the American Cancer Society 2015, women have a 12% chance of developing ...
Synthesis and characterization of zinc-doped magnetic nanoparticles for diagnostic studies
(University of the Western Cape, 2015)
In the present study we report the synthesis and characterization of iron oxide magnetic nanoparticles doped with zinc in an attempt to enhance the magnetic properties. The nanoparticles were prepared via the co-precipitation ...
In silico and molecular validation of identified putative genes and functional analysis of a N K G2D ligand as a breast cancer biomarkers
(University of the Western Cape, 2015)
The current diagnostic, prognostic, predictive and therapeutic monitoring methods
used for breast cancer are limited. Thus, research into more specific, sensitive and
effective strategies is required. Breast cancer is ...
An empowerment programme for women on breast self-examination towards the prevention of breast cancer in Iddo Local Government, Oyo State, South-west Nigeria
(University of the Western Cape, 2015)
Cancer is a major public health concern in both developed and developing countries; it accounts for 13% of all deaths globally, of which 70% occur in middle- and low-income countries. In Nigeria, over 10 000 cancer deaths ...
The development of nanotechnology-based detection systems for the diagnosis of breast cancer
(University of the Western Cape, 2015)
Breast cancer is one of the major causes of death in South Africa. About 1 in 29 South African women are at risk of developing this type of cancer in their lifetime. The global incidence of breast cancer also increases ...
The integrated effects of selected inducers of endoplasmic reticulum stress, the unfolded protein response and apoptosis on P-Glycoprotein mediated drug resistance in MCF-7 breast carcinoma cells
(University of the Western Cape, 2015)
Purpose: One of the leading causes of death reported in women worldwide is breast cancer. Manytumours, including breast cancer, associated with poor prognosis, have received a renewed focus and increased perspective with ...