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Effects of environmental growth conditions on the levels of sutherlandins 3 and 4 and sutherlandiosides B and D, in Sutherlandia frutescens (L.) R. Br.
(University of the Western Cape, 2011)
Sutherlandia frutescens (L.) R. Br. (Fabaceae), indigenous to the Western Cape region of South Africa, is found in a Mediterranean-type climate known for its many environmental stressors that can influence the levels of ...
Garlic and African olive used as traditional Herbs for hypertension in the Western Cape
(University of the Western Cape, 2012)
Hypertension is a common chronic health problem worldwide due to contributing factors such as obesity, physical inactivity, unhealthy diet and changes in lifestyle. The standard of care for hypertension in South Africa is ...
The effects of maternal diets, varying in fat content, on proximal hepatic and skeletal muscle insulin signalling in neonatal wistar rat offspring
(University of the Western Cape, 2013)
The incidence of type 2 diabetes (T2D) is persistently increasing globally. T2D is associated
with pancreatic β cell dysfunction and insulin resistance in peripheral tissues such as the liver
and skeletal muscle. Skeletal ...
Nitrogen and carbon costs of growth and antioxidant production during acclimation to environmental stress in two species of gethyllis
(University of the Western Cape, 2012)
Gethyllis multifolia L. Bolus and G. villosa Thunb. are winter-growing, summerblooming,deciduous and bulbous geophytes that grow naturally in the semi-arid succulent Karoo biome of South Africa. Both species grow under ...
The impact of storage time and seasonal harvesting on biomarker levels of lessertia frutescens
(University of Western Cape, 2012)
In South Africa, it is estimated that approximately 70% of the population frequently make use of traditional medicinal plants for their health care needs. The use of Lessertia frutescens by the various cultural groups in ...
The immune-modulating activity of Artemisia afra
(University of the Western Cape, 2010)
This study shows that herbs can be effectively screened for potiential bio-activity using in vitro methods. Further studies will be needed to better explore Artemisia afra’s effect on immunoregulation, particularly ...
Evaluation of the antioxidant and anti-diabesity potential of cyclopia maculata using in vitro non-cell based screening models
(University of the Western Cape, 2014)
The aim of this study was therefore to evaluate the antioxidant and anti-diabesity potential of a hot water extract of C. maculata in non-cell based assays and correlate the activities with phenolic composition. Total ...
The immune-modulating activity of Sutherlandia frutescens
(University of the Western Cape, 2010)
The aim of this study was to investigate the effects of Sutherlandia frutescens on the inflammatory response and T cell differentiation in vitro using cytokines as biomarkers. Whole blood cells containing various concentrations ...
An assessment of Hypoxis hemerocallidea extracts, and actives as natural antibiotic, and immune modulation phytotherapies
(University of the Western Cape, 2006)
In South Africa, the crude aqueous extract from Hypoxis hemerocallidea is used by AIDS patients to treat opportunistic infections, such as tuberculosis. The rapid emergence of multidrug-resistant tuberculosis, and extreme ...
Use of antioxidant activity and flavonoid levels to assess the quality of commercially available solid dose Sutherlandia frutescens products
(University of the Western Cape, 2010)
The overall aims of this project were to assess the pharmaceutical quality and consistency of commercially available solid dose Sutherlandia frutescens containing products (viz. tablets & capsules) by exploring the use of ...