Search
Now showing items 1-10 of 362
Aptamer selection against GFRa1 for its application in the prognosis of breast cancer
(University of the Western Cape, 2019)
Breast cancer is the second most common cancer amongst South African women. Despite
ongoing efforts to combat breast cancer, current prognostic and/or therapeutic monitoring
methods are limited since very little improvement, ...
Laccases from actinomycetes for lignocellulose degradation
(University of the Western Cape, 2012)
Lignocellulose has a complex structure composed mainly of lignin, hemicellulose and cellulose. Several enzymes are needed for the degradation of lignocellulose into simple sugars. Actinomycetes are known to produce laecases ...
The development of functionalized metallic nanoparticles for the treatment of brain cancer
(University of the Western Cape, 2019)
Cancers of the nervous system often result from abnormal and uncontrolled growth of cells in nervous tissue. Glioblastoma Multiforme (GBM) and neuroblastoma (NB) are among the most common nervous system-associated cancers ...
Novel gold nanoparticles of drought tolerance enabler GYY4137
(University of the Western Cape, 2019)
Different nanoparticles have the ability to improve plant tolerance to drought stress. In the study we report for the first time novel morpholin-4-ium 4-methoxyphenyl (morpholino) phosphinodithioate capped- gold nanoparticles ...
Comparative analysis of molecular and physiological responses of two canola genotypes to drought stress
(University of the Western Cape, 2016)
Food security has always been one of the priority concerns in Africa, and it is mostly
threatened by drought stress due to climate change. Drought-induced stress is one of the serious limiting factors of plant production, ...
Genome assembly of next-generation sequencing data for the Oryx bacillus : species of the Mycobacterium tuberculosis complex
(University of the Western Cape, 2011)
Next generation sequencing (NGS) technology platforms have accelerated ability to
produce completed genome assemblies. Recently, collaborators at Tygerberg Medical
School outsourced the sequencing of Oryx bacillus, a ...
Genetic mapping of fruit quality traits in apple (malus x domestica borkh.)
(University of the Western Cape, 2011)
Apple fruit quality is of utmost importance to apple farmers and breeders in the selection and commercialization of new cultivars. Fruit size, colour, texture, firmness and taste are all traits that affect the quality of ...
Diversity of Frankia associated with Morella species of the Cape floristic region of Southern Africa
(University of the Western Cape, 2016)
Frankia is one of two partners in the globally distributed N2-fixing actinorhizal symbiosis between this filamentous soil-dwelling actinomycete and almost 300 species of host plants from eight diverse angiosperm families. ...
Screening bacterial symbionts of marine invertebrates for ribosomally synthesized natural products
(University of the Western Cape, 2016)
Pharmaceutical research and development strategies rely on the constant discovery of novel natural products as potential drugs. Recent studies have shown that the
microorganisms associated with sponges are the true producers ...
Microbial diversity of the Namib Desert salt pans
(University of the Western Cape, 2015)
Salt pans are a characteristic feature of many dry deserts. The microbial communities inhabiting salt pans are thought to be particularly complex and are generally dominated by halophilic microorganisms. Although saline ...