Browsing School of Pharmacy by Title
Now showing items 6-25 of 224
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Additional regulatory review pathways can facilitate faster dossier approvals in South Africa
(University of the Western Cape, 2019)The objective of the study was to perform a comparative review of pathways, timelines and improvements of countries with markets that the South African Health Products Authority (SAHPRA) benchmark themselves against. ... -
Adverse effects experienced by patients on first line antiretroviral drugs used at Keetmanshoop Hospital (Namibia).
(University of the Western Cape, 2015)Adverse effects are a significant factor that determine how long patients will tolerate a given antiretroviral drug regimen. They also influence treatment options, and play an important role in the much needed adherence ... -
Adverse Foetal Outcomes in Gestational Diabetes: A Systematic Review and Meta-analysis
(University of the Western Cape, 2020)Gestational diabetes mellitus (GDM) is a condition that affects pregnant women and is one of the most common complications related to pregnancy. According to the World health organisation (WHO), the usual window for ... -
Adverse pregnancy outcomes among HIV-positive pregnant women treated with efavirenz-containing antiretroviral drugs: a retrospective cohort study in the Cape Flats
(University of the Western Cape, 2017)The use of efavirenz (EFV) in the first trimester of pregnancy remains controversial. In South Africa, the use of EFV-containing antiretroviral therapy (ART) as part of a Fixed Dose Combination (FDC) during the first trimester ... -
Analysis on access to antiretroviral therapy for patients with different income and educational level, and the effect of treatment on quality of life after two to three months of therapy
(University of the Western cape, 2017)Access to antiretroviral therapy (ART) for HIV positive patients has brought hope and a chance to a healthier longer life with improved quality of life (QoL). In this study we explored the difference in health related ... -
Antiasthmatic properties of Lippia javanica and Myrothamnus flabellifolius using an in vitro model
(University of the Western Cape, 2022)Asthma is a reversible, chronic inflammatory disease that causes obstruction to the airways that causes an increase in airway hyperresponsiveness that leads to recurrent episodes of chest tightness and coughing. Lippia ... -
Antimicrobial discovery from South African marine algae
(University of the Western Cape., 2018)Antimicrobials are chemical compounds that destroy or inhibit the growth of microorganisms. The majority of these antimicrobials are actually natural products or natural product derived with key examples being the pioneer ... -
The antimicrobial screening of four South African Asteraceae species and the preliminary structural investigation of an antipseudomonal compound from Arctotis auriculata
(University of the Western Cape, 1998)Infectious diseases represent one of the main causes of morbidity and mortality in developing countries, like South Africa. The indiscriminate use of antibiotics has also resulted in the emergence of a number of resistant ... -
The antimicrobial screening of four South African asteraceae species and the preliminary structural investigation of an antipseudomonal compound from Arctotts auriculata
(University of the Western Cape, 1998)Infectious diseases represent one of the main causes of morbidity and mortality in developing countries, like South Africa. The indiscriminate use of antibiotics has also resulted in the emergence of a number of resistant ... -
Aspects of the gastrointestinal uptake and metabolism of luteolin derivatives from Artemisia afra aqueous extract (preclinical)
(University of the Western Cape, 2011)The aim of this study was to investigate the effect the plant matrix and the structure of the flavonoid (i.e. whether aglycone or glycoside) may have on the gastrointestinal uptake and metabolism of luteolin derivatives ... -
Assessing the influence of electronic media on student perceptions towards antibiotic resistance
(University of the Western Cape, 2022)Antimicrobial resistance (AMR) and the reduced number of new antibiotic discoveries impose a major threat to the quality of human life and effective treatment options. Antibiotic resistant infections require prolonged ... -
An assessment of current practice patterns of TB/HIV at primary health care clinics in the Western Cape and a needs assessment for clinic-based training among final year pharmacy students
(University of the Western Cape, 2010)Tuberculosis and mv Tuberculosis (TB) is a major contributor to the disease burden in developing countries resulting in the deaths of approximately 2 million people a year. South Africa (SA) has one ( of the highest ... -
An assessment of current practice patterns of TB/HIV at primary healthcare clinics in the Western Cape and a needs assessment for clinic-based training among final year Pharmacy students
(University of the Western Cape, 2010)Tuberculosis (TB) is a major contributor to the disease burden in developing countries resulting in deaths of approximately 2 million people a year. South Africa (SA) has one of the highest annual TB incidences with an ... -
An assessment of current practice patterns of TB/HIV at primary healthcare clinics in the Western Cape and a needs assessment for clinic-based training among final year pharmacy students
(University of the Western Cape, 2010)Tuberculosis (TB) is a major contributor to the disease burden in developing countries resulting in deaths of approximately 2 million people a year. South Africa (SA) has one of the highest annual TB incidences with an ... -
An assessment of three Carpobrotus species extracts as potential antimicrobial agents.
(University of the Western Cape, 2001)For centuries, indigenous people in South Africa have used a variety of medicinal herbs to treat chronic infections. This investigation focused on three Carpobrotus species, in an attempt to assess their potential antimicrobial ... -
The availability of persons nominated for adverse drug reporting and associated challenges in Gauteng regional and district public hospitals
(University of the Western Cape, 2019)Background and Objectives: The reporting of adverse drug reactions (ADRs) is a major public health necessity. It is estimated that only six to 10 percent of all ADRs are reported worldwide. This number is far less than the ... -
Awareness regarding non-steroidal anti-inflammatory drug-related side effects in Johannesburg, South Africa
(University of Western Cape, 2021)Non-steroidal anti-inflammatory drugs (NSAIDs) are amongst the most commonly used medications globally, as they are highly effective and easily accessible. The NSAIDs are indicated for mild to moderate pain management. The ... -
Bioassay guided fractionation of Angiotensin converting enzyme inhibitor compound from Hypericum perforatum
(University of the Western Cape, 2019)Due to the contribution of hypertension to various cardiovascular diseases, many studies are currently focused on identifying efficient bioactive compounds with antihypertensive activity and thus reducing the levels of ... -
Biosimilar’s Growth in Pharmerging Markets: An Analysis of the Regulatory Environments
(University of the Western Cape, 2020)The introduction of biosimilars to health care markets across the globe has had some success in increasing competition and improving the cost of healthcare. While savings are important for driving the biosimilar uptake, ... -
Cannabidiol: A medicine, health supplement or foodstuff? Analysis of South African policies relating to the introduction of cannabidiol into the market
(University of the Western Cape, 2022)With the recent rise in the popularity of cannabidiol (CBD) around the world, there are many cultivators, manufacturers, and sellers of CBD on the market. It is sold in different dosage forms including oils, used to treat ...