Browsing School of Pharmacy by Title
Now showing items 55-74 of 228
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Design, implementation and evaluation of a model for service-learning in pharmacy (slip) at a Tertiary hospital
(2009)Background In recent years the focus of pharmacy practice has changed from being primarily ‘drugcentred to’ one which is ‘patient-centred’ (El-Awady et al., 2006, p.1). Developments in pharmacy curricula worldwide are ... -
The design, preparation and evaluation of Artemisia Afra and placebos in tea bag dosage form suitable for use in clinical trials
(University of the Western Cape, 2006)Artemisia Afra, a popular South African traditional herbal medicine is commonly administered as a tea infusion of the leaves. However, clinical trials proving it safety and efficacy are lacking mainly due to the absence ... -
Design, Synthesis and Evaluation of Indole Derivatives as Multifunctional Agents against Alzheimer's disease.
(University of the Western Cape, 2017)Alzheimer's disease (AD) is an age related neurodegenerative disorder characterised by progressive memory loss and cognitive impairment. It is one of several neurodegenerative disorders occurring as a result of a process ... -
Determination of kanamycin plasma concentrations using LC/MS and pharmacokinetics of kanamycin in patients with multidrug-resistant tuberculosis and in patients with multidrug-resistant tuberculosis co-infected with HIV
(University of the Western Cape, 2012)The aim of the study was to determine firstly, kanamycin plasma concentrations using liquid chromatography coupled with mass spectrometry (LC/MS); secondly, to investigate the PK parameters of kanamycin in patients infected ... -
Determination of plasma concentrations using Lc/ms and pharmacokinetics of ofloxacin in Patients with multi-drug resistant tuberculosis and In patients with multi-drug resistant tuberculosis co- Infected with hiv
(University of the Western Cape, 2009)Many studies have investigated the pharmacokinetics of anti-tuberculosis drugs in patients infected with tuberculosis. However, little is known about the pharmacokinetics of the drugs that are used in the treatment of ... -
Determination of plasma concentrations using LC/MS and pharmacokinetics of ofloxacin in patients with multi-drug resistant tuberculosis and in patients with multi-drug resistant tuberculosis coinfected with hiv
(2009)Many studies have investigated the pharmacokinetics of anti-tuberculosis drugs in patients infected with tuberculosis. However, little is known about the pharmacokinetics of the drugs that are used in the treatment of ... -
Determination of pyrazinamide plasma concentrations using lc-ms and pharmacokinetics of pyrazinamide in patients with multidrug-resistant tuberculosis and in patients co-infected with multidrug-resistant tuberculosis and HIV
(2013)Tuberculosis and HIV are arguably South Africa’s largest and most important health issues. With drug-resistant strains of tuberculosis on the increase and little research on new drugs, there is an urgent need for research ... -
The development and evaluation of the Objective Structured Dispensing Examination (OSDE) for use in an undergraduate pharmacy training programme
(University of the Western Cape, 2004) -
Development of a model to predict the cost of management of diabetes mellitus and its complications at Groote Schuur Hospital
(University of the Western Cape, 2012)Diabetes mellitus places a substantial financial burden on the funder for treatment of this disease. This burden is compounded by the development of diabetes mellitus related complications. The cost of management of diabetes ... -
Development of a model to predict the cost of treatment of breast cancer with chemotherapy at Groote Schuur hospital
(University of the Western Cape, 2017)In South Africa, breast cancer dominates other forms of cancer affecting women in both prevalence and mortality rates according to the National Cancer Registry. The incidence and cost of breast cancer have been on the rise ... -
Development of rifampicin loaded in surface-modified 4.0 G PAMAM dendrimer as a novel antituberculosis pulmonary drug delivery system
(University of the Western Cape, 2020)Introduction: Tuberculosis (TB) is a serious bacterial infections caused by the Mycobacterium Tuberculosis (MTB) organism affecting mainly the lungs. Occasionally, MTB bacilli may be transported out of the pulmonary region ... -
Development, implementation and evaluation of a diabetes educational outreach inervention for pharmacists
(University of the Western Cape, 2007)Increasing diabetes prevalence rates, poor involvement of and limited knowledge among health care professionals in disease management, and poor implementation of guidelines are barriers to quality diabetes care. This thesis ... -
The development, implementation and evaluation of an integrated framework for undergraduate pharmacy education in maternal and child health at the University of the Western Cape
(University of the Western Cape, 2022)The high rate of maternal and child mortality is a global health concern. Nationally, it is one of South Africa’s quadruple disease burdens. The Sustainable Development Goal 3, 2030 targets related to maternal and child ... -
Discovery of anti-mycobacterial natural products from South African marine algae
(University of the Western Cape, 2019)Tuberculosis is a communicable disease which affects millions of people around the world. Although the case reports are declining, the eradication rate of this disease is far too slow. Natural products have played a key ... -
Discovery of antibacterial lead compounds from marine organisms
(University of the Western Cape, 2020)Marine organisms including algae and bacteria are known to produce chemically diverse secondary metabolites for survival purposes in the marine environment. Scientists have identified some of these natural products as ... -
Discovery of cytotoxic natural products from South African marine sponges
(University of the Western Cape, 2018)Cancer is a major health problem worldwide and killing millions of people each year. The use of natural products as chemotherapeutic agents is well established, however, many of the currently available drugs are associated ... -
Discovery of heat shock protein90 inhibitors using structured-based virtual screening
(University of the Western Cape, 2023)Alzheimer's disease (AD) is the most common irreversible dementia, caused by accumulation of protein aggregates in the central nervous system, with symptoms that include memory loss and behavioural abnormalities. Cholinesterase ... -
Disposal of unused medicines from households in Cape Town
(University of Western Cape, 2019)Evidence indicates that most South African households do not dispose of unused medicines in the manner prescribed by the medicine’s regulatory authority. This trend is not unique to South Africa, but several developing ... -
Disposal Practices for Unwanted Medicines from Households in Johannesburg
(University of the Western Cape, 2017)A mixed research method was used where quantitative research facilitated qualitative research. Three questionnaires were drafted and distributed by email to respondents in the Johannesburg area. One questionnaire was for ... -
Dissolution and antiviral activity of a novel nevirapine formulation
(University of the Western Cape, 2014)The author’s objective was to follow the product life-cycle process of a novel antiretroviral, nevirapine formulation in South Africa, to generate and compile data to pursue market registration. Five supramolecular ...