Browsing School of Pharmacy by Title
Now showing items 63-82 of 228
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Development of a model to predict the cost of management of diabetes mellitus and its complications at Groote Schuur Hospital
(University of the Western Cape, 2012)Diabetes mellitus places a substantial financial burden on the funder for treatment of this disease. This burden is compounded by the development of diabetes mellitus related complications. The cost of management of diabetes ... -
Development of a model to predict the cost of treatment of breast cancer with chemotherapy at Groote Schuur hospital
(University of the Western Cape, 2017)In South Africa, breast cancer dominates other forms of cancer affecting women in both prevalence and mortality rates according to the National Cancer Registry. The incidence and cost of breast cancer have been on the rise ... -
Development of rifampicin loaded in surface-modified 4.0 G PAMAM dendrimer as a novel antituberculosis pulmonary drug delivery system
(University of the Western Cape, 2020)Introduction: Tuberculosis (TB) is a serious bacterial infections caused by the Mycobacterium Tuberculosis (MTB) organism affecting mainly the lungs. Occasionally, MTB bacilli may be transported out of the pulmonary region ... -
Development, implementation and evaluation of a diabetes educational outreach inervention for pharmacists
(University of the Western Cape, 2007)Increasing diabetes prevalence rates, poor involvement of and limited knowledge among health care professionals in disease management, and poor implementation of guidelines are barriers to quality diabetes care. This thesis ... -
The development, implementation and evaluation of an integrated framework for undergraduate pharmacy education in maternal and child health at the University of the Western Cape
(University of the Western Cape, 2022)The high rate of maternal and child mortality is a global health concern. Nationally, it is one of South Africa’s quadruple disease burdens. The Sustainable Development Goal 3, 2030 targets related to maternal and child ... -
Discovery of anti-mycobacterial natural products from South African marine algae
(University of the Western Cape, 2019)Tuberculosis is a communicable disease which affects millions of people around the world. Although the case reports are declining, the eradication rate of this disease is far too slow. Natural products have played a key ... -
Discovery of antibacterial lead compounds from marine organisms
(University of the Western Cape, 2020)Marine organisms including algae and bacteria are known to produce chemically diverse secondary metabolites for survival purposes in the marine environment. Scientists have identified some of these natural products as ... -
Discovery of cytotoxic natural products from South African marine sponges
(University of the Western Cape, 2018)Cancer is a major health problem worldwide and killing millions of people each year. The use of natural products as chemotherapeutic agents is well established, however, many of the currently available drugs are associated ... -
Discovery of heat shock protein90 inhibitors using structured-based virtual screening
(University of the Western Cape, 2023)Alzheimer's disease (AD) is the most common irreversible dementia, caused by accumulation of protein aggregates in the central nervous system, with symptoms that include memory loss and behavioural abnormalities. Cholinesterase ... -
Disposal of unused medicines from households in Cape Town
(University of Western Cape, 2019)Evidence indicates that most South African households do not dispose of unused medicines in the manner prescribed by the medicine’s regulatory authority. This trend is not unique to South Africa, but several developing ... -
Disposal Practices for Unwanted Medicines from Households in Johannesburg
(University of the Western Cape, 2017)A mixed research method was used where quantitative research facilitated qualitative research. Three questionnaires were drafted and distributed by email to respondents in the Johannesburg area. One questionnaire was for ... -
Dissolution and antiviral activity of a novel nevirapine formulation
(University of the Western Cape, 2014)The author’s objective was to follow the product life-cycle process of a novel antiretroviral, nevirapine formulation in South Africa, to generate and compile data to pursue market registration. Five supramolecular ... -
Efavirenz pre-formulation study : selection of a cyclodextrin inclusion complex or co-crystal complex for tabletting
(University of the Western Cape, 2015)Efavirenz is a non-nucleoside reverse transcriptase inhibitor used as an anti-retroviral for the treatment of human immunodeficiency virus (HIV) type I. It is classified as a class IΙ drug under the Biopharmaceutical ... -
The effect of co-crystallization and polymorphism on the physicochemical properties of amoxicillin tri-hydrate
(University of the Western Cape, 2013)Many active pharmaceutical ingredients (APIs) have poor physicochemical properties such as solubility, dissolution and chemical stability. Several strategies are used to enhance and improve these properties of the API. ... -
The effect of dossier farming on medicine registration in South Africa.
(University of the Western Cape, 2020)In this study, the researcher wanted to determine the effect of dossier farming in medicine registration in South Africa by comparing the number of generic registrations of products tendered for the government for the ... -
Effect of inhaled cationic poly-peptides on respiratory mechanics in the isolated perfused rat lung
(University of the Western Cape, 1998)The inhalation route is increasingly being considered as a viable option to deliver protein drugs into the body, but there has been few studies dealing with the safety of this strategy. The results of in vitro studies have ... -
Effect of Tulbaghia violacea on the blood pressure and heart rate in male spontaneously hypertensive wistar rats
(University of the Western Cape, 2011)Tulbaghia violacea Harv. (Alliaceae) is a small bulbous herb which belongs to the family, Alliaceae, most commonly associated with onions and garlic. In South Africa (SA), this herb has been traditionally used in the ... -
The effectiveness of using pictograms and text on medication labels at primary healthcare facilities in Cape Town
(University of the Western Cape, 2020)Medication labels are often the only information available to patients after obtaining medication 3 from the pharmacy or other healthcare practitioners. Inappropriately designed medicine labelling 4 contributes to poor ... -
Effects of Leonotis leonorus aqueous extract on the isolated perfused rat heart
(University of the Western Cape, 2007)An aqueous extract prepared from the leaves and smaller stems of Leonotis leonorus was used to investigate the potential effects on certain cardiovascular parameters such as left ventricular systonic pressure, end-diastolic ... -
Effects of Leonotis leonurus aqueous extract on the isolated perfused rat heart
(University of the Western Cape, 2007)An aqueous extract prepared from the leaves and smaller stems of Leonotis leonurus was used to investigate the potential effects on certain cardiovascular parameters, such as left ventricular systolic pressure, end-diastolic ...