Browsing School of Pharmacy by Issue Date
Now showing items 21-40 of 228
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Neuropharmacological profile of Mentha longifolia: Effects on convulsion, nociception and pentobarbitone-induced sleep in mice
(University of the Western Cape, 2004)Mentha longifolia Huds., subspecies, capensis Briq, a plant species used for the treatment of epilepsy, painful conditions such as headache and toothache, and insomnia amongst other ailments, was investigated for anticonvulsant, ... -
Effects of the alkaloid present in the ethyl acetate: hexane (1 :4) fraction of Crinum macowanii on the isolated perfused rat heart
(University of the Western Cape, 2004)Crinum macowanii (CM) is used in traditional medicine in the treatment of various diseases including ischemic heart disease, rheumatic fever, cancer and skin diseases. The aqueous extract of CM bulbs was found have a ... -
The evaluation of markers for quality control studies of flavonoid-containing medicinal preparations
(University of the Western Cape, 2004)In spite of the high utilization of South African traditional medicine, the therapeutic potential and the chemical components of many plant preparations are unknown. For the safe and effective use of these medicinal ... -
Pharmacological evaluation of some central nervous system effects of Cotyledon Orbiculata
(University of the Western Cape, 2005)The use of traditional medicine through the use of medicinal plants in Africa and especially in South Africa has long been considered an important characteristic of people's daily lives and socio-cultural heritage. Cotyledon ... -
Acute and chronic toxicity of the flavonoid-containing plant, Artemisia afra in rodents
(University of the Western Cape, 2005)The aim of this study was to investigate the possible toxicity of the flavonoid-containing plant, Artemisia afra and especially establish the safety of the aqueous extract of this plant after acute and chronic administration ... -
Evaluation of guidelines for clinical trials of traditional plant medicines
(University of the Western Cape, 2005)The World Health Organization estimates that 4 billion people use herbal medicine for some aspect of primary health care. These herbal products are however mostly used without the necessary clinical trial done to prove ... -
The formulation, manufacture and evaluation of capsules containing freeze-dried aqueous extracts of Leonotis Leonorus or Mentha Longifolia
(University of the Western Cape, 2006)Leonotis leonorus and Mentha longifolia are two herbs commonly used in South Africa, mostly in oral liquid dosage forms. Several disadvantages are associated with these traditional dosage forms which can perhaps be remedied ... -
The design, preparation and evaluation of Artemisia Afra and placebos in tea bag dosage form suitable for use in clinical trials
(University of the Western Cape, 2006)Artemisia Afra, a popular South African traditional herbal medicine is commonly administered as a tea infusion of the leaves. However, clinical trials proving it safety and efficacy are lacking mainly due to the absence ... -
An investigation into the relationship between personality type, as measured by the Keirsey Bates Temperament Sorter, choice of practice setting and job satisfaction of pharmacists who graduated from the University of the Western Cape over the period 1990-2005
(University of the Western Cape, 2006)For the study the Keirsey Bates Temperament Sorter was completed by 602 pharmacy students during their study period at the University of the Western Cape. The results showed that the pharmacy students had a tendency towards ... -
Evaluation of the pulmonary effects of the traditionally prepared Artemisia afra steam inhalation and nebulized aqueous extract and the possible involvement of flavonoid luteolin
(University of the Western Cape, 2006)Artemisia afra is a popular medicinal plant traditionally used to treat respiratory conditions such as asthma, bronchitis etc., most frequently as a steam inhalation. The effectiveness of this steam inhalation, its active ... -
The evaluation of microwave drying on the polymorphic characteristics of carbamazepine granules prepared by the wet granulation process.
(Univeraity of the Western Cape, 2006)The drying conditions of granules for tabletting prepared by the wet granulation process traditionally involve conduction, convection and radiation heat transfer. Despite various technological advances utilizing combinations ... -
A comparative study of the phosphodiesterase 4 inhibitory activity of artemisia afra, Leonotis leonorus and mentha longifolia plant medicines
(University of the Western Cape, 2007)The specific objectives of this study were to investigate whether Artemisia Afra, Leonotis leonorous and Mentha Longiflora have PDE 4 inhibitory activity, to determine and compare the levels of the total phenolic compunds ... -
Expanding presumptive male partner management of sexually transmitted infections (STIs) to Western Cape, South African community retail pharmacies
(University of the Western Cape, 2007)The effect of industrialisation has thrust the pharmaceutical profession into a clinical paradigm where the approcah to pharmaceutical decisions is more disease and patient orientated. Consequently, South African community ... -
Development, implementation and evaluation of a diabetes educational outreach inervention for pharmacists
(University of the Western Cape, 2007)Increasing diabetes prevalence rates, poor involvement of and limited knowledge among health care professionals in disease management, and poor implementation of guidelines are barriers to quality diabetes care. This thesis ... -
Effects of Leonotis leonorus aqueous extract on the isolated perfused rat heart
(University of the Western Cape, 2007)An aqueous extract prepared from the leaves and smaller stems of Leonotis leonorus was used to investigate the potential effects on certain cardiovascular parameters such as left ventricular systonic pressure, end-diastolic ... -
Effects of Leonotis leonurus aqueous extract on the isolated perfused rat heart
(University of the Western Cape, 2007)An aqueous extract prepared from the leaves and smaller stems of Leonotis leonurus was used to investigate the potential effects on certain cardiovascular parameters, such as left ventricular systolic pressure, end-diastolic ... -
Cardiovascular effects of aqueous leaf extract of Leonotis leonurus in Anesthetized rats
(University of the Western Cape, 2008)The present study was designed to evaluate the hypotensive properties and the mechanisms of action of the aqueous leaf extract of Leonotis leonurus in anesthetized male Wistar rats, using computerized blood pressure ... -
Design, implementation and evaluation of a model for Service-learning in Pharmacy (SLIP) at a tertiary hospital
(University of the Western Cape, 2009)In recent years the focus of pharmacy practice has changed from being primarily 'drug-centred to' one which is 'patient-centred' (El-Awady et al., 2006, p. l ). Developments in pharmacy curricula worldwide are reflecting ... -
Cardiovascular effects of (13S)-9_, 13_- epoxylabda-6_(19), 15(14)diol dilactone, a diterpenoid isolated from the organic extract of leonotis leonurus leaves, in anaesthetized normotensive rats
(2009)Plants used in traditional medicines have served as sources of some of the drug compounds used in medicines today, and could still serve as leads for then development of new drugs to treat existing chronic diseases such ... -
Determination of plasma concentrations using LC/MS and pharmacokinetics of ofloxacin in patients with multi-drug resistant tuberculosis and in patients with multi-drug resistant tuberculosis coinfected with hiv
(2009)Many studies have investigated the pharmacokinetics of anti-tuberculosis drugs in patients infected with tuberculosis. However, little is known about the pharmacokinetics of the drugs that are used in the treatment of ...