Browsing School of Pharmacy by Subject "Mycobacterium tuberculosis"
Now showing items 1-5 of 5
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Discovery of anti-mycobacterial natural products from South African marine algae
(University of the Western Cape, 2019)Tuberculosis is a communicable disease which affects millions of people around the world. Although the case reports are declining, the eradication rate of this disease is far too slow. Natural products have played a key ... -
Discovery of antibacterial lead compounds from marine organisms
(University of the Western Cape, 2020)Marine organisms including algae and bacteria are known to produce chemically diverse secondary metabolites for survival purposes in the marine environment. Scientists have identified some of these natural products as ... -
Ethionamide pharmacokinetics in multidrugresistant tuberculosis patients with and without HIVinfection
(University of the Western Cape, 2017)Many studies have investigated the pharmacokinetics (PK) of anti-tuberculosis drugs in tuberculosis patients. However, currently in South Africa, no studies have been done on ethionamide (ETH) PK in adult MDR-TB patients ... -
Evaluation of selected polycyclic compounds as resistance modulators in Mycobacterium tuberculosis
(University of the Western Cape, 2022)Progressive development of resistance to various chemotherapeutic agents used in the management of infectious diseases presents a serious problem in global public health. Increasing levels of antimicrobial resistance in ... -
Treatment outcomes in patients infected with multidrug resistant tuberculosis and in patients with multidrug resistant tuberculosis coinfected with human immunodeficiency virus at Brewelskloof Hospital
(University of the Western Cape, 2012)Many studies have reported low cure rates for multidrug-resistant tuberculosis (MDRTB) patients and MDR-TB patients co-infected with human immunodeficiency virus (HIV). However, little is known about the effect of HIV ...