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Now showing items 31-40 of 68
Monitoring lipid and haematological abnormalities in paediatric patients on antiretroviral therapy at a Community Health Centre in the Cape Metropole
(University of the Western Cape, 2014)
South Africa faces a huge Human Immunodeficiency Virus (HIV) burden with more than 400,000 children currently on antiretroviral therapy (ART). Studies on lipid and haematological profile changes in paediatrics are of ...
Novel tricycloundecane derivatives as potential N-methyl-Daspartate receptor and calcium channel inhibitors for neuroprotection
(University of the Western Cape, 2014)
This study focused on the synthesis of a series of novel tricycloundecane derivatives and evaluation of these compounds for neuroprotection using the fluorescent ratiometric calcium assay that indicates the ability of the ...
The impact an accredited third party assessor will have on the regulator’s response time
(University of the Western Cape, 2014)
Globally regulators have been under scrutiny for delays in market application (MA) approvals. The main issue that surfaces in studies related to these delays is a shortage in competent reviewers. The concept of a third ...
An assessment of current practice patterns of TB/HIV at primary healthcare clinics in the Western Cape and a needs assessment for clinic-based training among final year Pharmacy students
(University of the Western Cape, 2010)
Tuberculosis (TB) is a major contributor to the disease burden in developing countries resulting in deaths of approximately 2 million people a year. South Africa (SA) has one of the highest annual TB incidences with an ...
Examining the inventory management of antiretroviral drugs at community health centres in the cape metropole, Western Cape
(2013)
South Africa is faced with a high number of people living with HIV/AIDS, and
subsequently a great need to access quality medicines for improving patient therapeutic outcomes. Antiretroviral drugs (ARVs) require rigid, ...
Inter-professional collaboration between general practitioners and community pharmacists: general practitioners’ perspectives
(University of Western Cape, 2012)
The global movement towards enhancing inter-professional collaboration in patient
care is in light of the increasing potency of drugs and complexity of drug regimens,
particularly in the chronically ill where poly-pharmacy ...
Treatment outcomes in patients infected with multidrug resistant tuberculosis and in patients with multidrug resistant tuberculosis coinfected with human immunodeficiency virus at Brewelskloof Hospital
(University of the Western Cape, 2012)
Many studies have reported low cure rates for multidrug-resistant tuberculosis (MDRTB) patients and MDR-TB patients co-infected with human immunodeficiency virus (HIV). However, little is known about the effect of HIV ...
Determination of pyrazinamide plasma concentrations using lc-ms and pharmacokinetics of pyrazinamide in patients with multidrug-resistant tuberculosis and in patients co-infected with multidrug-resistant tuberculosis and HIV
(2013)
Tuberculosis and HIV are arguably South Africa’s largest and most important health issues. With drug-resistant strains of tuberculosis on the increase and little research on new drugs, there is an urgent need for research ...
Pharmaceutical evaluation of phela capsules Used as traditional medicine
(University of the Western Cape, 2010)
In conclusion, the results obtained firstly indicated that the BP, EMEA and WHO were in fairly good agreement on the criteria and specifications that can be used to assesses the pharmaceutical quality of a traditional plant ...
Evaluation of antihistamines for in vitro antimalarial activity against Plasmodium falciparum
(2010)
The declining efficacy of antimalarial drugs against resistant Plasmodium falciparum strains in several endemic regions has amplified the world’s burden of neglected diseases. This has highlighted the need for alternate ...