Browsing Magister Scientiae - MSc (Biotechnology) by Title
Now showing items 212-231 of 270
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Peptide functionalised gold nanorods for the selective eradication of target cells using photothermal therapy
(University of the Western Cape, 2019)Cancer is one of the leading causes of death, worldwide. Mortality tolls are estimated to reach approximately 13.1 million in 2030. These statistics suggest that current therapeutic strategies are not effective. This is ... -
Phylogenetic diversity of nifH genes in Marion Island soil
(University of the Western Cape, 2006)The microbial life of sub-Antarctic islands plays a key role in the islands ecosystem, with microbial activities providing the majority of nutrients available for primary production. Knowledge of microbial diversity is ... -
Physio-biochemical characterization of two wheat cultivars to Fusarium proliferatum infection
(University of the Western Cape, 2019)Wheat is a key global commodity in terms of acreage and tradeable value and as a staple in household diets. Many factors including biotic stress conditions have detrimental effects on global wheat production and yield. ... -
Physiological and biochemical characterization, of antimony stress, responses in Phaseolus vulgaris
(University of the Western Cape, 2018)The mining industry in South Africa is of immense importance as this sector contributes largely to the countries income. In the Limpopo province, a large production of antimony (Sb) is generated per year. Antimony (Sb) is ... -
Physiological and cellular characterization of a plant natriuretic peptide
(University of the Western Cape, 2005)Plants in the field are exposed to multiple stresses and their response to these various stresses determines their capacity to survive. Plants can use multiple signaling pathways and signals to mediate their response; for ... -
Physiological and molecular characterization of wheat cultivars to Fusarium oxysporum infection
(University of the Western Cape, 2019)Biotic stress is one of the main causes for agricultural loss of economically important cereal crops. The increasing prevalence of biotic stress inflicted by fungal species such as Fusarium has significantly reduced yields ... -
Phytochemical and antimicrobial studies on Rhus natalensis
(2011)Extracts from the root bark, stem bark, and leaves of R. natalensis were screened for antibacterial activity against standard bacterial strains; Staphylococcus aureas, Escherichia coli and Pseudomonas aureginosa, and fungi; ... -
Polyethylene glycol (PEG) induced water stress alters the physiological and molecular responses of chia plants
(The University of the Western Cape, 2017)Water deficit is known to be one of the most detrimental environmental factors to affect crop production and growth in South Africa. This factor has become more apparent with increasing cases of drought in the country. -
The prevalence and survival of Campylobacter, Salmonella and Listeria species in poultry processing plant
(University of the Western Cape, 2004)The organisms in this study were chosen due to their associations with foods and their potential as food borne pathogens. Food borne diseases are an import public health problem in most countries. Bacteria of the genera ... -
Prevalence of uncontrolled hypertension and the pharmacogenomics of enalapril-induced adverse effects among patients in the Vhembe district
(University of the Western Cape, 2022)Controlling blood pressure (BP) among individuals with hypertension is important in the prevention of cardiovascular diseases (CVDs). However, maintaining optimal BP levels in individuals who are prone to drug-induced ... -
Proteome signature of breast cancer cells treated with fucoidan
(University of the Western Cape, 2016)Breast cancer is responsible for a large portion of cancer-related deaths. Worldwide, incidence is increasing. Routinely-used treatments for breast cancer are invasive and are associated with a range of side-effects which ... -
Proteomic and SNP analysis of the Cadherin 10 type-II (CDH10) gene, in the South African autistic population
(University of the Western Cape, 2013)Autism or autism spectrum disorder (ASD) is a very diverse neurological disorder that manifests specifically in children and infants between the ages of two to three years of age. An individual suffering is deemed as ... -
Proteomic characterisation of wine yeast strains for the expression of arginases involved in urea formation during fermentation
(University of the Western Cape, 2018)Wine is a fermented beverage widely consumed all over the world as a recreational drink, but is known for its health benefits to humans. However, wine contain urea, a by-product of arginine hydrolysis by arginases expressed ... -
Recombinant expression and full backbone assignment of the human DWNN using heteronuclear NMR
(University of the Western Cape, 2005)The cellular levels of a number of proteins have been found to be regulated by the ubiquitin-proteasome pathway. In this pathway, proteins are covalently tagged (“ubiquitinated”) by ubiquitin, which acts as a signal for ... -
Recombinant expression of cytochrome P450-2D6 and its application in tamoxifen metabolism
(University of the Western Cape, 2018)Breast cancer is regarded as the most common form of cancer in women and it comprises of approximately 23 % of female cancers, while affecting women at any age range. For oestrogen receptor positive patients, tamoxifen is ... -
Recombinant expression of the pRb- and p53-interacting domains from the human RBBP6 protein for in vitro binding studies
(University of the Western Cape, 2004)This thesis describes the cloning and recombinant expression of domains from the human RBBP6 protein for future in vitro binding studies with pRb and p53. RBBP6 is a splicing-associated protein that is known to interact ... -
Recombinant expression of the pRb- and p53-interacting domains from the human RBBP6 protein for in vitro binding studies
(University of the Western Cape, 2004)This thesis describes the cloning and recombinant expression of domains from the human RBBP6 protein for future in vitro binding studies with pRb and p53. RBBP6 is a splicing-associated protein that is known to interact ... -
Reconstruction of major male and female lineages of the kensington Muslim community
(University of the Western Cape, 2010)The earliest Cape Muslims were brought to the Cape from Africa and Asia from 1652 to 1834. They were part of an involuntary migration of slaves, political prisoners and convicts, and they contributed in the ethnic diversity ... -
Reconstruction of major male and female lineages of the Strand Muslim community
(University of the Western Cape, 2010)Initially, a pilot study was carried out in order to reconstruct the major paternal and maternal lineages of the Muslim population living in the Cape metropolitan area. The Study has shown the ability of molecular genetic ... -
Response of microbial communities to synthetic winery wastewater in biological sand filters
(University of the Western Cape, 2017)There has been a significant increase in the use of constructed wetlands globally for the bioremediation of wastewater (Welz et al., 2011). In South Africa, the wine industry generates more than one billion litres of ...