Browsing Magister Scientiae - MSc (Biotechnology) by Author "Benjeddou, Mongi"
Now showing items 1-11 of 11
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Development and validation of a pharmacogenomics profiling panel suitable for personalizing metformin therapy
Xhakaza, Lettilia (University of the Western Cape, 2019)The burden of non-communicable diseases (NCDs) in South Africa is predicted to increase substantially in the next decades if the necessary preventative measures are not taken. The two most common NCDs associated with ... -
Development and validation of a pharmacogenomics profiling panel suitable for personalizing Metformin therapy
Xhakaza, Lettilia (University of the Western Cape, 2019)The burden of non-communicable diseases (NCDs) in South Africa is predicted to increase substantially in the next decades if the necessary preventative measures are not taken. The two most common NCDs associated with rapid ... -
Development and validation of Non-CODIS miniSTR genotyping systems suitable for forensic case work in South Africa
Abrahams, Zainonesa (University of the Western Cape, 2010)The objective of this study was to develop and validate a six Non-CODIS miniSTR genotyping system and to determine its suitability for forensic casework in South Africa. In Non-CODIS miniSTR genotyping systems, smaller PCR ... -
Development of genotyping systems for pharmacogenomics profiling
Eshumani, Fatima A. (University of the Western Cape, 2016)Genetic variability in genes encoding drug metabolizing enzymes, transporters and targets are known to be the main factors of inter-individual differences in therapeutic outcome. Genetic factors are estimated to be responsible ... -
Development of Y-STR genotyping systems suitable for sexual assault cases in South Africa
Cloete, Kevin Wesley (University of the Western Cape, 2010)Sexual assault is a significant problem facing the South African society. In this context, efficient but also affordable genotyping systems are needed for positive identification of criminals in incidences of sexual violence. ... -
Genetic diversity of the Organic Cation Transporter 1 gene within the Cape Coloured Population
Pearce, Brendon (University of the Western Cape, 2012)The aim of this study was to investigate the genetic diversity of the SLC22A1 gene and to deduce its possible pharmacogenetic implications within the Cape Coloured population of South Africa; a uniquely admixed population ... -
In vitro evaluation of Leonotis leonurus to validate its potential as an alternative anti-diabetic drug
Sigodi, Yolanda (University of the Western Cape, 2022)Africa is a rich source of medicinal plants with South Africa being known as a country with a strong history of traditional healing, which masses a variety of approximately 30 000 flowering plants and accounting for ... -
Nanoformulation of Artemisia afra and its potential biomedical applications in type 2 diabetes
Liebenberg, Nicole Albertha-Wade (University of Western Cape, 2019)Current research classifies Type 2 diabetes as most prevalent non-communicable diseases in South Africa. Approximately 285 million people are affected globally with an expected increase to 595 million by the year 2035. ... -
Prevalence of uncontrolled hypertension and the pharmacogenomics of enalapril-induced adverse effects among patients in the Vhembe district
Musoliwa, Rendani (University of the Western Cape, 2022)Controlling blood pressure (BP) among individuals with hypertension is important in the prevention of cardiovascular diseases (CVDs). However, maintaining optimal BP levels in individuals who are prone to drug-induced ... -
Reconstruction of major male and female lineages of the kensington Muslim community
Isaacs, Shafieka (University of the Western Cape, 2010)The earliest Cape Muslims were brought to the Cape from Africa and Asia from 1652 to 1834. They were part of an involuntary migration of slaves, political prisoners and convicts, and they contributed in the ethnic diversity ... -
Reconstruction of major male and female lineages of the Strand Muslim community
Geduld, Tasneem (University of the Western Cape, 2010)Initially, a pilot study was carried out in order to reconstruct the major paternal and maternal lineages of the Muslim population living in the Cape metropolitan area. The Study has shown the ability of molecular genetic ...