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Investigation into the role of DWNN in cell death
(University of the Western Cape, 2004)
Many genes are activated to influence the self-destruction programme of the cell. This programme entails synchronised instigation and implementation of numerous subprograms. The arrival of gene targeting aided in the ...
The genease activity of mung bean nuclease: fact or fiction?
(University of the Western Cape, 2004)
The action of Mung Bean Nuclease (MBN) on DNA makes it possible to clone intact gene fragments from genes of the malaria parasite, Plasmodium. This “genease” activity has provided a foundation for further ...
Microbial diversity of Antarctic Dry Valley mineral soil
(University of the Western Cape, 2004)
Antarctica provides some of the most extreme environments on earth. Low temperatures, low water availability and nutrient deficiency are contributing factors to the limited colonisation of Antarctic biotopes, particularly ...
The prevalence and survival of Campylobacter, Salmonella and Listeria species in poultry processing plant
(University of the Western Cape, 2004)
The organisms in this study were chosen due to their associations with foods and their potential as food borne pathogens. Food borne diseases are an import public health problem in most countries. Bacteria of the genera ...
Human testis angiotensin-converting enzyme: crystal structure of a glycosylation mutant and investigation of a putative hinge-mechanism by normal mode analysis
(University of the Western Cape, 2004)
Human angiotensin-converting enzyme (ACE) is a key enzyme in the
regulation of blood pressure via the renin-angiotensin and kallikrein-kinin
systems. A number of orally active drugs have been developed over the
years ...
Recombinant expression of the pRb- and p53-interacting domains from the human RBBP6 protein for in vitro binding studies
(University of the Western Cape, 2004)
This thesis describes the cloning and recombinant expression of domains from the human RBBP6 protein for future in vitro binding studies with pRb and p53. RBBP6 is a splicing-associated protein that is known to interact ...
Recombinant expression of the pRb- and p53-interacting domains from the human RBBP6 protein for in vitro binding studies
(University of the Western Cape, 2004)
This thesis describes the cloning and recombinant expression of domains from the human RBBP6 protein for future in vitro binding studies with pRb and p53. RBBP6 is a splicing-associated protein that is known to interact ...
Ancient Genes in Cancer Gene Expression?
(University of the Western Cape, 2004)
Backsround: The Cancer/testis (CT) antigens are a division of germ cell specific genes not expressed in somatic cells, exceptions being placental cells and 20Vo - 4OVo of cancer types. The aptitude of CT antigens to elicit ...
Isolation and identification of PNP-A homologues from Xerophyta viscosa Baker
(University of the Western Cape, 2004)
Maintenance of growth, development and normal physiological processes remains crucial
for the survival of plants. Plant hormones are described as integrators of external signal
and internal developmental process in plants. ...
An investigation of the plants used medicinally In self-care in the Bredasdorp / Elim region
(University of the Western Cape, 2004)
Much of the traditional medicinal plant knowledge is to a large extent known by the
older generations. This knowledge is at risk of disappearing due to not being passed
down to younger members of the respective families ...