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Now showing items 141-150 of 169
Isolation and characterization of plant growth promoting endophytic bacteria from Medicago lupulina for enhanced drought tolerance in Maize
(University of the Western Cape, 2019)
Maize is one of the major staple foods in many African nations however, this crop is sensitive to environmental stressors. Drought is a major environmental stressor affecting maize production. Due to global warming, drought ...
Investigation of the auto-ubiquitination and ubiquitination potentials of Retinoblastoma binding protein 6 and its binding to p53
(University of Western Cape, 2019)
Retinoblastoma Binding Protein 6 (RBBP6) is a 200 kDa human protein known to play an
essential role in mRNA 3’-end processing, as well as functioning as an E3 ligase to catalyze
ubiquitination and suppression of p53 and ...
Investigation of protein-protein interactions involving retinoblastoma binding protein 6 using immunoprecipitation and nuclear magnetic resonance spectroscopy
(University of Western Cape, 2019)
Retinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa multi-domain protein that has been
shown to play a role in mRNA processing, cell cycle arrest and apoptosis. RBBP6 interacts with
tumour suppressor proteins such as ...
Development of an aptamer based lateral flow test strip for a diabetes biomarker
(University of the Western Cape, 2019)
Diabetes mellitus is one of the major chronic diseases that poses a significant risk to human
health globally. Current diagnostics for diabetes are based on blood glucose measurements,
which can go unnoticed for years. ...
Investigation of protein-protein interactions involving Retinoblastoma Binding Protein 6 using immunoprecipitation and Nuclear Magnetic Resonance Spectroscopy
(University of the Western Cape, 2019)
Retinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa multi-domain protein that has been
shown to play a role in mRNA processing, cell cycle arrest and apoptosis. RBBP6 interacts with
tumour suppressor proteins such as ...
Effects of exogenous myristic acid on growth and germination of Brassica napus L. under zirconium toxicity
(University of the Western Cape, 2016)
Lipids when exogenously applied are known to cause various changes in ROS
levels produced within plants. They can either be beneficial to the plant when not
stimulating the overproduction of ROS thus resulting in improved ...
Identification and validation of putative therapeutic and diagnostic antimicrobial peptides against HIV: An in silico approach
(University of the Western Cape, 2013)
Background: Despite the effort of scientific research on HIV therapies and to reduce the rate of HIV infection, AIDS still remains one of the major causes of death in the world and mostly in Sub-Saharan Africa. To date, ...
Characterization of ATP-binding cassette drug transporters and their role in breast cancer treatment using in silico approach
(University of the Western Cape, 2019)
Breast cancer is the most common cancer in women worldwide, and is the second most common cancer in the world, responsible for more than 500 000 deaths annually. Estimates are that 1 in 8 women will develop breast cancer ...
Isolation and characterization of stem endophytic bacteria from weed plants for enhancing Vanadium tolerance in Brassica napus
(University of the Western Cape, 2019)
Bacterial endophytes are able to improve the growth of their hosts through a number of
different mechanisms such as nutrient uptake regulation, plant hormone production and
regulation, siderophore production and phosphate ...
A comparative ancestry analysis of Y-chromosome DNA haplogroups using high resolution melting
(University of the Western Cape, 2018)
The objective of this study is to deduce paternal ancestry using ancestry
informative single nucleotide polymorphisms (SNPs) by means of High
Resolution Melting (HRM). This was completed by producing a multiplex system
that ...