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Phenotypic and molecular characteristics of Methicillin-resistant Staphylococcus Aureus isolates from stored patient samples in Misurata hospitals and poultry from commercial markets, Libya
(University of the Western Cape, 2019)
The emergence of virulent and drug-resistant bacterial strains such as methicillin-resistant
Staphylococcus aureus (MRSA) is a global public health burden. The World Health
Organization (WHO) has placed MRSA and ...
An evaluation of cancer biomarkers in normal ovarian epithelial cells and ovarian cancer cell lines
(University of the Western Cape, 2019)
Introduction: Globally, there are over 190,000 new reported cases of ovarian cancers per annum. This comprises 3% to 4% of all cancers in women. Ovarian cancer is one of the leading causes of deaths in women. Ovarian cancer ...
Ursolic acid and oleanolic acid as novel therapeutic agents in breast cancer
(University of the Western Cape, 2015)
Breast cancer is one of the most common cancers among women in South Africa and the second leading cause of cancer death after lung cancer. According to the American Cancer Society 2015, women have a 12% chance of developing ...
The frequency and characterization of streptococci in aerobic vaginitis (AV) and its association with pregnancy outcomes
(University of the Western Cape, 2014)
The aim of the study was to detect the prevalence of AV and its associated bacteria with preterm delivery in the Western Cape, South Africa. Furthermore, it sought particularly to examine and investigate the predictive ...
Modulation of colon carcinogenesis by dietary ω-6/ω-3 fatty acid ratios : a chemopreventive strategy?
(University of the Western Cape, 2015)
The aim of this study was to determine whether dietary fats constituting specific ω-6/ω-3 fatty acids (FA) ratio has chemopreventive modulating effects on the development of colon cancer. Western diets intake of saturated ...
Effects of Libyan traditional plants on the reproductive system of male and female rats
(University of the Western cape, 2015)
In different parts of the world, medicinal plants have demonstrated a lot of health benefits to mankind and remains an important source for the discovery of new bio-active compounds. Libya is a typical example of a country ...
Structural and functional characterization of human DDX5 and its interaction with NS5B of hepatitis C virus
(University of the Western Cape, 2011)
Hepatitis C was first recognized as a transfusion-associated liver disease not caused by hepatitis A or hepatitis B virus after serological tests were developed to screen for their presence in the blood. The infectious ...
Bionomics of vector-borne diseases in sites adjacent to lakes Victoria and Baringo in Kenya
(University of the Western Cape, 2016)
Bionomics of vector-borne pathogens (VBPs) is a complex phenomenon that involves understanding the ecology of arthropod borne pathogens and vertebrate hosts potentially involved in their transmission cycles. Investigations ...
The effect of maternal exposure to alcohol and nicotine on pancreas and kidney size, aorta and carotid intima thickness and visceral fat in their children.
(University of Western Cape, 2019)
In utero exposure to teratogens, increasing urbanization, rapid nutritional transition from poverty to affluence, adoption of a Western-style diet and physical inactivity have contributed to the growing obesity epidemic ...
Synergistic effects of mixtures of fungicides and medicinal plant extracts against Botrytis cinerea
(University of the Western Cape, 2008)
We hypothesize that South African medicinal plants contain compounds that can act in synergism with synthetic antifungal compounds. Four fungicides - Sporekill™, Rovral™,
Terminator™ and Teldor™ at doses 0.1, 0.2, 0.4 and ...