Novel adamantane-chloroquinolin conjugates to overcome plasmodium falciparum chloroquine resistance
Abstract
Malaria poses devastating health and socioeconomic outcomes on global health especially
among pregnant women and children below the age of 5 in endemic areas. This is
exacerbated by Plasmodium falciparum resistance to available antimalarial drugs, especially
chloroquine (CQ), which was the drug of choice for many years against the blood stage of
malaria.