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A framework for the analysis of discrete irregular patterned sequential datasets
(University of the Western Cape, 2023)
Trial-and-error is often used for developing new deep learning models. There is no systematic procedure for improving existing models for predicting irregular sequential time-series. This research developed a systematic ...
An assessment of river and wetland morphology dynamics using geospatial techniques
(University of the Western Cape, 2023)
Land surface modification has intensified in recent years, and it continues to be an ongoing process. This raises serious concerns about changes in land use and land cover (LULC) since some of these changes have led to ...
Structural features of air-processible methyl ammonium lead triiodide (MAPbI3) perovskite thin films grown on Al-doped ZnO Nanowire Arrays
(University of the Western Cape, 2023)
The performance of air stable, mixed halide (MAPbI3-xClx) perovskite based solar cells is highly dependent on the quality and stability of the perovskite thin film, which in turn, is dependent on the substrate on which it ...
Mathematical modeling of the population dynamics and optimal control of COVID-19 disease
(2024)
Since the onset of the COVID-19 pandemic, researchers speculated that this virus would create numerous challenges in the daily lives of individuals, especially medical and governmental authorities as they are put under ...
The effect of doxorubicin encapsulated chitosan alginate nanoparticles and curcumin on multidrug resistant colon cancer cell lines
(University of the Western Cape, 2024)
Purpose: Although chemotherapeutic drugs have improved the survival rate of patients diagnosed with colorectal cancer, resistance to chemotherapy frequently leads to therapeutic failure and poor patient outcomes. Multidrug ...
Identification of potential antibiofilm hit compounds from two African natural product database against multi-drug resistant staphylococcus aureus: an in silico study
(University of the Western Cape, 2023)
One of the crucial ways by which Staphylococcus aureus develops resistance to antibiotics is biofilm formation, a protective mechanism involving extracellular polymeric substance (EPS) matrix that shields microorganisms ...
Reptile community responses to an avian ecosystem engineer
(University of the Western Cape, 2023)
In the Kalahari, sociable weavers (Philetairus socius) build huge, communal nests. Although Kalahari tree skinks (Trachylepis spilogaster) are known to preferentially use trees that host such colonies, the degree to which ...
The transition of regulatory services from drug regulatory unit to Botswana medicines regulatory authority: an evaluation of the changes in regulatory services from the industry’s perspective
(University of the Western Cape, 2023)
The Drug Regulatory Unit (DRU) was established by the Ministry of Health (MoH) to enforce the Drugs and Related Substances Act of 1992 in line with the Botswana National Drug Policy (BNDP) adopted in 2002 and the National ...
A categorical study of persistent homology for closure space
(University of the Western Cape, 2023)
We begin with the concept of closure space and show how it relates to other objects like graphs and metric spaces in categorical terms. We also study the notion of simplicial sets and show that there is an adjunction between ...
The formulation of a microsphere based fixed dose combination for oral antiretroviral delivery
(University of the Western Cape, 2023)
The cost of providing antiretroviral therapy (ART) remains a significant economic burden on African countries due to poverty and a lack of resources. To reduce the economic burden of HIV infection, a formulation scientist ...