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The impact of nanoparticles on the proteome of cultured human cells
(2021)
Living organisms are constantly being exposed to nanoparticles (NPs) in the environment via air,
water, soil. Routes of exposure are usually in the form of industrial, occupational exposure, as well
as therapeutic ...
The development of targeting nanosystems for the treatment of glioblastoma and neuroblastoma tumours
(University of the Western Cape, 2022)
Chlorotoxin (CTX) peptide selectively targets glioblastoma multiforme (GB) and
neuroblastoma (NB) and has excellent blood-brain barrier permeability. Therefore, CTX is a
promising targeting molecule for nanoparticle (NP) ...
Synthesis and characterization of magneto-electric nanoparticles for delivery of antituberculosis drugs across the blood-brain barrier
(University of the Western Cape, 2022)
The anatomical structure of the brain at the blood–brain barrier (BBB) creates a limitation for the
movement of drugs into the central nervous system (CNS). Although anti-infective drugs effective
against Mycobacterium ...
The effect of doxorubicin encapsulated chitosan alginate nanoparticles and curcumin on multidrug resistant colon cancer cell lines
(University of the Western Cape, 2024)
Purpose: Although chemotherapeutic drugs have improved the survival rate of patients diagnosed with colorectal cancer, resistance to chemotherapy frequently leads to therapeutic failure and poor patient outcomes. Multidrug ...