The formulation and evaluation of indomethacin tablets
Abstract
The overall objective of this research is to attempt to produce, by direct compression,
indomethacin tablets which have good dissolution characteristics and an improved
bioavailability profile, when compared to the capsule formulations currently available. In
order to use the direct compression method, the solubilized form of indomethacin should
have good flow properties, as well as a small bulk volume for incorporation into reasonably
sized tablets.