Browsing Magister Scientiae - MSc (Medical BioSciences) by Title
Now showing items 131-150 of 159
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A quantitative and qualitative assessment of dental aerosols within a dental clinical unit: An avenue for the transmission of resistant nosocomial infection.
(University of Western Cape, 2020)Introduction: Nosocomial infections are infections that occur 48 hours after receiving care for an unrelated condition in a clinic or a hospital environment, many of which are resistant to at least one of the drugs most ... -
Radioprotective effects of rooibos herbal tea on the developing central nervous system of wistar rats
(University of the Western Cape, 2018)Background: Early postnatal radiation exposure from environmental, diagnostic or therapeutic sources is potentially deleterious to the developing nervous system resulting in oxidative stress, structural damage, altered ... -
Radiosensitization effects of gold nanoparticles in proton therapy
(University of the Western Cape, 2017)Despite recent advances in radiotherapy, some tumours have shown to be resistant to treatment and patients still experience long term side effects. Gold nanoparticles (AuNPs) have been identified as effective radiosensitizers ... -
Red palm oil as a therapeutic agent in triple-negative breast cancer patients
(University of the Western Cape, 2020)Purpose: Breast cancer is one of the most frequent and fatal diseases women all around the globe are challenged with today. In women, breast cancer has the highest mortality rate of all cancers and the incidence rate is ... -
The relationship between male genital tract infection, oxidative status in the ejaculate, and apoptotic markers in human spermatozoa
(2009)Aim: Leukocytes are the major source of reactive oxygen species (ROS) in the ejaculate and contribute to up to 30% of male infertility. ROS have been associated with markers of apoptosis such as sperm DNA damage, ... -
The role of c-reactive protein as a marker for preterm delivery
(University of Western Cape, 2020)Pregnancy associated maternal morbidity and mortality along with adverse pregnancy outcomes have gained momentum over the past few years, particularly in Sub-Saharan Africa and Southern Asia despite the advances in medical ... -
Screening of Selected Libyan Medicinal Plants for the Synthesis of Metal Nanoparticles and their activity against Streptococcus mutans
(University of the Western Cape, 2020)Nanotechnology has emerged as an elementary division of modern science and stemmed directly from green chemistry twelve basic concepts, it receives global attention due to its unique character and ample applications. It ... -
Seasonal differences in semen characteristics and sperm functionality in Tankwa goats
(University of the Western Cape, 2018)Tankwa goats have been free-ranging in the Tankwa Karoo National Park in the Northern Cape for more than 80 years. A genetic study concluded that these feral goats are a unique genetic resource compared to other goat breeds ... -
Structural and functional aspects of sperm after transit through the fallopian tube of the sheep
(University of the Western Cape, 1996)Ejaculated mammalian spermatozoa have the potential for fertilization. The acquisition of the ability to fertilize a fully invested oocyte occurs during the passage through the female reproductive tract. These post-ejaculatory ... -
Student experiences of life science practicals
(UWC, 2001)Science Educationists seem to agree that practical work should form an important component of any science course. Many students arrive at University without having been exposed to any practical work, while others were ... -
Synthesis and applications of functionalized pyridinyl imine complexes of palladium
(University of the Western Cape, 2005)The synthesis and characterization of pyridinyl α-diimine Pd(II) complexes having a functionalized hydrocarbon attached to the imino nitrogen was performed. The catalytic activity of these complexes were then evaluated in ... -
Synthesis and characterization of magneto-electric nanoparticles for delivery of antituberculosis drugs across the blood-brain barrier
(University of the Western Cape, 2022)The anatomical structure of the brain at the blood–brain barrier (BBB) creates a limitation for the movement of drugs into the central nervous system (CNS). Although anti-infective drugs effective against Mycobacterium ... -
The effects of selective inhibitors of N-Glycosylation and Endoplasmic Reticulum stress inducers on Neuroblastoma cell proliferation and Apoptosis
(University of the Western Cape, 2017)Among all childhood cancers diagnosed, neuroblastoma (NB) is the most prevalent during infancy. In patients younger than 15 years, it accounts for more than 7% of malignancies and about 15% of all paediatric mortalities. ... -
The effects of selective inhibitors of n-glycosylation and endoplasmic reticulum stress inducers on the expression of neuroblastoma drug resistance
(University of the Western Cape, 2017)Neuroblastoma (NB) represents 8-10% of all childhood tumours and accounts for approximately 15% of all cancer-related deaths in the paediatric population. Approximately half of newly diagnosed children with this tumour ... -
The evaluation of the cardioprotective effects of Olea containing liposomes
(University of the Western Cape, 2017)High levels of free oxygen radicals, induced by many biological or environmental factors, result in damage and dysfunction of the mitochondria which causes cardiovascular and other diseases. Cardiotherapies employing antioxidants ... -
The Generation of Antibodies against Human Coronavirus NL63 (HCoV-NL63) Nucleocapsid Protein
(University of the Western Cape, 2017)Coronaviruses (CoVs) are enveloped viruses composed of single-stranded, positive sense RNA viruses with the largest viral genomes among RNA viruses (27-33 kb). In 2004, human coronavirus NL63 (HCoV-NL63) was discovered by ... -
The role of arylamine N-acetyltransferase 1 (NAT1) in the clinical therapy of tuberculosis
(University of the Western Cape, 2017)Despite attempts to develop new drugs to reduce the worldwide mortality rate attributable to tuberculosis (TB), the illness remains a threat. Isoniazid (INH) has been used as a frontline drug for decades. However, several ... -
The role of the glutathione system in regulating the levels of ROS neutralisation in the endothelial cells of the blood-brain barrier
(University of the Western Cape, 2017)Brain endothelial cell types are frequently used as in vitro models to study the blood-brain barrier (BBB). Oxidative stress (OS) has been reported numerous times to cause BBB dysfunction which is crucial to the initiation ... -
The use of in vitro assays to screen for endocrine modulation
(University of the Western Cape, 2008)Aspalathus linearis (A. linearis), commonly known as Rooibos tea or Red bush tea and Camellia sinensis (C. sinensis) or Black tea are beverages that are consumed throughout the world. These teas possess antioxidant, ...