Browsing by Subject "Natural products"
Now showing items 1-14 of 14
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Antimicrobial discovery from South African marine algae
(University of the Western Cape, 2018)Antimicrobials are chemical compounds that destroy or inhibit the growth of microorganisms. The majority of these antimicrobials are actually natural products or natural product derived with key examples being the pioneer ... -
Biochemical investigation of anti-cancer activity of Tulbaghia violacea
(UWC, 2012)Natural products have been a source of many pharmaceutical drugs and a number of drugs that are currently used in the treatment of cancer are derivatives of compounds originally isolated from natural products. There is ... -
Cheminformatic Approaches to Hit-Prioritization and Target Prediction of Potential Anti-MRSA Natural Products
(University of the Western Cape, 2020)The growing resistance of Methicillin-Resistant Staphylococcus aureus (MRSA) to currently prescribed drugs has resulted in the failure of prevention and treatment of different infections caused by the superbug. Therefore, ... -
Cheminformatic approaches to hit-prioritization and target prediction of potential anti-mrsa natural products
(University of Western Cape, 2020)The growing resistance of Methicillin-Resistant Staphylococcus aureus (MRSA) to currently prescribed drugs has resulted in the failure of prevention and treatment of different infections caused by the superbug. Therefore, ... -
Computational strategies to identify, prioritize and design potential antimalarial agents from natural products
(University of the Western Cape, 2015)Introduction: There is an exigent need to develop novel antimalarial drugs in view of the mounting disease burden and emergent resistance to the presently used drugs against the malarial parasites. A large amount of natural ... -
Discovery of anti-mycobacterial natural products from South African marine algae
(University of the Western Cape, 2019)Tuberculosis is a communicable disease which affects millions of people around the world. Although the case reports are declining, the eradication rate of this disease is far too slow. Natural products have played a key ... -
Discovery of antibacterial lead compounds from marine organisms
(University of the Western Cape, 2020)Marine organisms including algae and bacteria are known to produce chemically diverse secondary metabolites for survival purposes in the marine environment. Scientists have identified some of these natural products as ... -
Investigation of the natural products composition from the seaweed ulva capensis
(University of Western Cape, 2019)In modern society, diversity of marine macroalgae has become an inspiration for pharmaceutical companies and researchers because of their numerous health benefits, and a great deal of interest has developed towards the ... -
The isolation and characterisation of novel natural products from marine bacterial symbionts
(University of the Western Cape, 2015)Drug-resistant infections are a global health crisis and drastically hinder the treatment options to effectively combat disease. Today, natural products remain an important source of novel drug candidates. Micro-organisms, ... -
Isolation and characterization of natural products from selected Rhus species
(University of Western Cape, 2020)Searsia is the more recent name for the genus (Rhus) that contains over 250 individual species of flowering plants in the family Anacardiaceae. Research conducted on Searsia extracts to date indicates a promising potential ... -
Screening extracts of indigenous South African plants for the presence of anti-cancer compounds
(University of the Western Cape, 2006)Early man dabbled with the use of plant extracts to cure ailments. This practice has been passed down from generation to generation and today more than 50% of the world'sdrugs are natural products or derivatives thereof. ... -
Screening of natural products and alkylating agents for antineoplastic activity
(2007)Apoptosis is a process in which a cell programmes its own death. It is a highly organized physiological mechanism in which injured or damaged cells are destroyed. Apart from physiological stimuli however, exogenous factors ... -
Screening of natural products and alkylating agents for antineoplastic activity
(University of the Western Cape, 2007)Background and objectives: Apoptosis is a process in which a cell programmes its own death. It is a highly organized physiological mechanism in which injured or damaged cells are destroyed. Apart from physiological stimuli ... -
Secondary metabolites of the uromycladium tepperianum macalpine epiphytic fungus
(University of the Western Cape, 2021)Research on natural products and medicinal plants has been conducted more with each passing year due to the great interest in isolating bioactive compounds and secondary metabolites from natural products such as plants, ...