Biological and enzymatic activity of actinobacteria associated with aloe ferox

Abstract

Antimicrobial resistance is a global crisis that has been on the rise for decades, threatening the health and safety of many nations. This highlights the need to discover novel antimicrobial compounds to combat already resistant pathogens, as well as newly emerging pathogens. Historically soil bacteria, particularly actinobacteria, have been a source of novel bioactive compound, however, the constant re-isolation of known actinobacterial strains led to the need to explore unique environments. Higher plants, especially medicinal plants, represent a unique niche for the isolation of rare, bioactive actinobacterial species.