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Metagenomic analysis and characterization of microbial diversity from hydrothermal samples of El Tatio geyser field, Chile
(University of the Western Cape, 2012)
The El Tatio geyser field (ETGF) is the largest known geothermal field in Chile, forming part of a wide spectrum of extremophilic habitats in the country. The ETGF is NaCl rich, with high concentrations of toxic elements ...
Design and synthesis of polycyclic amine derivatives for sigma receptor activity
(2013)
New therapeutic strategies are needed for a diverse array of poorly understood neurological impairments. These include neurodegenerative disorders such as Parkinson’s disease and Alzheimer’s disease, and the psychiatric ...
Investigating novel cis-acting regulatory elements involved in the regulation of heat shock response in cardiomyocytes
(2013)
Ischemic heart disease is a disease which is characterized by the reduced blood
supply to the heart. According to WHO 2013, ischemic heart disease is one of the
major causes of death globally. For this reason, it is ...
Seasonal dynamics of edaphic bacterial communities in the hyper-arid namib desert
(2012)
The Namib Desert is a hyper-arid, coastal desert with limited bioavailable water and
nutrients; characteristics which collectively impose constraints on edaphic microbial
communities. Several studies in the Namib Desert ...
Investigation of the intra-cellular localisation of Retinoblastoma Binding Protein 6 using immunofluorescence microscopy
(University of the Western Cape, 2017)
Human Retinoblastoma Binding Protein 6 (RBBP6) is a 200 kDa protein that has been
implicated in a number of crucial cellular processes. It forms part of the mRNA 3'-end
processing complex in both humans and yeast, and it ...
Bacillus licheniformis isolated from Mozambican soil capable of producing 2, 3-butanediol
(The University of the Western Cpae, 2018)
Due to the current fossil fuel sources rapidly depleting as a result of the increased global need,
alternative, sustainable and renewable sources are required. Biofuels, which are environmentally
friendly, meet all the ...
Tungsten Telluride Quantum dot-based Biosensor for Alpha-Methylacyl CoA Racemase – An Emerging Prostate Cancer Biomarker
(University of the Western Cape, 2019)
Prostate cancer, commonly referred to as adenocarcinoma of the prostate, is the leading cause of cancer death in men in 46 countries, and it was estimated that by the end of 2018 there would approximately be 1.3 million ...
Genomic instability in South African breast cancer patients
(2013)
Breast cancer (BC) is one of the most common malignancies in women. Death results from treatment failure and metastatic disease. Thousands of lives might be saved if it was possible to detect and eliminate occult metastatic ...
Electrochemical Aptasensing of B-Type Natriuretic Peptide-A Biomarker for Myocardial Infarction
(University of the Western Cape, 2019)
infarction (MI) affects many parts of the western world and in South Africa alone it is estimated that MI is responsible for 1 in 6 deaths (17.3%). Traditional diagnostic methods for MI include an electrocardiograms and ...
Green synthesis and characterization of silver nanoparticles (AgNPs) from Bulbine frutescens leaf extract and their antimicrobial effects.
(University of the Western Cape, 2020)
Combating antimicrobial resistant infections caused by nosocomial pathogens poses a major public health problem globally. The widespread use of broad-spectrum antibiotics for the treatment of wound infections has led to ...