Browsing Magister Scientiae - MSc (Bioinformatics) by Author "Faculty of Science"
Now showing items 1-8 of 8
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Assessment of genome visualization tools relevant to HIV genome research: development of a genome browser prototype
Boardman, Anelda Philine (University of the Western Cape, 2004)Over the past two decades of HIV research, effective vaccine candidates have been elusive. Traditionally viral research has been characterized by a gene -by-gene approach, but in the light of the availability of complete ... -
Computational verification of published human mutations
Kamanu, Frederick Kinyua (University of the Western Cape, 2008)The completion of the Human Genome Project, a remarkable feat by any measure, has provided over three billion bases of reference nucleotides for comparative studies. The next, and perhaps more challenging step is to analyse ... -
The development of a single nucleotide polymorphism database for forensic identification of specified physical traits
Naidu, Alecia Geraldine (University of the Western Cape, 2009)Many Single Nucleotide Polymorphisms (SNPs) found in coding or regulatory regions within the human genome lead to phenotypic differences that make prediction of physical appearance, based on genetic analysis, potentially ... -
High performance computing and algorithm development: application of dataset development to algorithm parameterization
Jonas, Mario Ricardo Edward (University of the Western Cape, 2006)A number of technologies exist that captures data from biological systems. In addition, several computational tools, which aim to organize the data resulting from these technologies, have been created. The ability of these ... -
HIV subtype C diversity: analysis of the relationship of sequence diversity to proposed epitope locations
Ernstoff, Elana Ann (University of the Western Cape, 2002)Southern Africa is facing one of the most serious HIV epidemics. This project contributes to the HIVNET, Network for Prevention Trials cohort for vaccine development. HIVÂ’s biology and rapid mutation rate have made vaccine ... -
Incidence and regulatory implications of single Nucleotide polymorphisms among established ovarian cancer genes
Ramdayal, Kavisha (University of the Western Cape, 2009)OVARIAN cancer research focuses on answering important questions related to the disease, determining whether new approaches are feasible to contribute towards improving current treatments or discovering new ones. This study ... -
A knowledgebase of stress reponsive gene regulatory elements in arabidopsis Thaliana
Adam, Muhammed Saleem (University of the Western Cape, 2011)Stress responsive genes play a key role in shaping the manner in which plants process and respond to environmental stress. Their gene products are linked to DNA transcription and its consequent translation into a response ... -
miRNAMatcher: High throughput miRNA discovery using regular expressions obtained via a genetic algorithm
Duvenage, Eugene (University of the Western Cape, 2008)In summary there currently exist techniques to discover miRNA however both require many calculations to be performed during the identification limiting their use at a genomic level. Machine learning techniques are currently ...