| dc.contributor.advisor | Van Wyk, Brian | |
| dc.contributor.author | Soko, White | |
| dc.contributor.other | School of Public Health | |
| dc.contributor.other | Faculty of Community and Health Sciences | |
| dc.date.accessioned | 2013-08-02T13:52:09Z | |
| dc.date.available | 2011/10/20 11:40 | |
| dc.date.available | 2011/10/20 | |
| dc.date.available | 2013-08-02T13:52:09Z | |
| dc.date.issued | 2010 | |
| dc.identifier.uri | http://hdl.handle.net/11394/1790 | |
| dc.description | Magister Public Health - MPH | en_US |
| dc.description.abstract | Aim: To determine and compare the prevalence of CCR5-Δ32 and CCRV64I genes in HIV positive and HIV negative population of pregnant women from Harare, in Zimbabwe. Results: The proportion of pregnant women with the homozygous CCR2V64I gene was 24.38% and this gene was two times more associated with HIV infection than in those without it ( RR= 2.32, 95% CI-1.38-3.92). No CCR5-Δ32 deletion was detected in the studied population. Conclusion: The homozygous CCR2V64I gene and STIs were more prevalent in HIV infected pregnant women than in uninfected pregnant women and no homozygousCCR5-Δ32 gene was detected in this study. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | University of the Western Cape | en_US |
| dc.subject | HIV in pregnant women | en_US |
| dc.subject | Host genetic factors | en_US |
| dc.subject | Gene polymorphism | en_US |
| dc.subject | Mutation | en_US |
| dc.subject | Protective effect | en_US |
| dc.subject | CCR5-Δ32 | en_US |
| dc.subject | CCR2V64 | en_US |
| dc.subject | Vaccines | en_US |
| dc.subject | Chemotherapeutic drugs | en_US |
| dc.subject | Zimbabwe | en_US |
| dc.title | Frequency of CCR2V64I and CCR5Δ32 host genes and their association with HIV infection among pregnant women from Harare, Zimbabwe | en_US |
| dc.type | Thesis | en_US |
| dc.rights.holder | University of the Western Cape | en_US |
| dc.description.country | South Africa | |
