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Solution structure of the RING finger domain from the human splicing-associated protein RBBP6 using heteronuclear Nuclear Magnetic Resonance (NMR) spectroscopy
(2009)
Retinoblastoma-binding protein 6 (RBBP6) is a multi-domain human protein known to play a role in mRNA splicing, cell cycle control and apoptosis. The protein interacts with tumour suppressor proteins p53 and pRb and recent ...
A yeast 2-hybrid screen to identify and characterize interaction partners of the cancer associated protein retinoblastoma binding protein 6
(2009)
Retinoblastoma binding protein 6 (RBBP6) is a 250 kDa protein that is
implicated in mRNA processing and ubiquitination functions and has been
shown to be highly up-regulated in a number of cancers. In humans and mice,RBBP6 ...
Molecular detection and characterisation of RNA viruses of honeybees
(University of the Western Cape, 2009)
Propagation methods for honeybee viruses have not changed since these viruses were discovered. There are no suitable cell lines or cell culture techniques available for honeybee viruses. Honeybee viruses have to be manually ...
Transcription regulation and candidate diagnostic markers of esophageal cancer
(University of the Western Cape, 2009)
Esophageal cancer (EC) ranks among the ten most frequent cancers worldwide. Mortality rates associated with EC are very similar to the incidence rates due to the relatively late stage of diagnosis and the poor efficacy of ...
A proteomic analysis of drought and salt stress responsive proteins of different sorghum varieties
(University of the Western Cape, 2009)
This study reports on a proteomic analysis of sorghum proteomes in response to salt and hyperosmotic stresses. Two-dimensional gel electrophoresis (2DE) in combination with mass spectrometry (MS) was used to separate, ...
Characterisation of AtPNP-A - a novel arabidopsis thaliana gene with role in water and salt homeostasis
(University of the Western Cape, 2009)
Plant natriuretic peptides (PNPs) are a novel class of extracellular, systemically mobile molecules that elicit a number of plant responses important in homeostasis and growth. Natriuretic peptides were first identified ...
Plant natriuretic peptides - elucidation of the mechanisms of action
(University of the Western Cape, 2009)
Several lines of cellular and physiological evidence have suggested the presence of a novel class of systemically mobile plant molecules that are recognized by antibodies generated against vertebrate atrial natriuretic ...
Identification of bacterial pathogenic gene classes subject to diversifying selection
(University of the Western Cape, 2009)
Availability of genome sequences for numerous bacterial species comprising of different bacterial strains allows elucidation of species and strain specific adaptations that facilitate their survival in widely fluctuating ...
Functional genomic characterization of fruit quality traits in apple (Malus x domestica Borkh)
(University of the Western Cape, 2009)
The domesticated apple (Malus x domestica Borkh), belonging to the Malusgenus of the Rosaceae family, is one of the edible pomaceous fruits. Since it is one of the important commercial fruit crops worldwide, the quality ...
Molecular detection and characterisation of RNA viruses of honeybees
(University of the Western Cape, 2009)
Honeybees have evolved through the centuries to inhabit most parts of the world except for the extreme Polar Regions. These insects have also been susceptible to pathogens and disease which has always been part of the ...