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Now showing items 11-20 of 28
Saturation sequencing, characterisation and mapping of the NBS-LRR resistance gene family in apple, Malus x domestica (Borkh)
(University of the Western Cape, 2008)
To date five classes of resistance proteins have been identified in plants and these include the intracellular protein kinases, receptor-like protein kinases with extracellular leucinerich repeat (LRR) domain, LRR proteins ...
Characterisation of AtPNP-A - a novel arabidopsis thaliana gene with role in water and salt homeostasis
(University of the Western Cape, 2009)
Plant natriuretic peptides (PNPs) are a novel class of extracellular, systemically mobile molecules that elicit a number of plant responses important in homeostasis and growth. Natriuretic peptides were first identified ...
Mining a Chinese hyperthermophilic metagenome
(University of the Western Cape, 2007)
Metagenomic sequencing of environmental samples provide direct access to
genomic information of organisms within the respective environments. This
sequence information represents a significant resource for the identification ...
Characterisation of microbial communities associated with hypolithic environments in Antarctic Dry Valley soils
(University of the Western Cape, 2008)
The Eastern Antarctic Dry Valley region is a polar desert, where conditions of extreme aridity, high temperature fluctuations and high irradiation levels make it one of the most extreme environments on earth. Despite the ...
Plant natriuretic peptides - elucidation of the mechanisms of action
(University of the Western Cape, 2009)
Several lines of cellular and physiological evidence have suggested the presence of a novel class of systemically mobile plant molecules that are recognized by antibodies generated against vertebrate atrial natriuretic ...
Identification of bacterial pathogenic gene classes subject to diversifying selection
(University of the Western Cape, 2009)
Availability of genome sequences for numerous bacterial species comprising of different bacterial strains allows elucidation of species and strain specific adaptations that facilitate their survival in widely fluctuating ...
Microbial diversity and gene mining in Antarctic Dry Valley mineral soils
(University of the Western Cape, 2006)
Soil communities are regarded as among the most complex and diverse assemblages of microorganisms with estimated bacterial numbers in the order of 109-1 cells.g. Studies on extreme soils however, have reported lower cell ...
Metagenomic approaches to gene discovery
(University of the Western Cape, 2006)
The classical approach to gene discovery has been to culture micro-organisms demonstrating a specific enzyme activity and then to recover the gene of interest through shotgun cloning. The realization that these standard ...
Identification and characterisation of a novel gene, DWNN, isolated from promoter-trapped Chinese hamster ovary cells
(University of the Western Cape, 2005)
The process of cytotoxic T lymphocyte (CTL) killing involves the recognition and destruction of foreign antigens by cytotoxic T cells and is of crucial importance to the defence of the organism against viral infections. ...
Structure, enzymology and genetic engineering of Bacillus sp. RAPc8 nitrile hydratase
(University of the Western Cape, 2005)
Microbial nitrile hydratases (NHases) are important industrial enzymes that catalyse the conversion of nitriles to the corresponding amides. A thermostable, cobalt-type
Bacillus sp. RAPc8 NHase was previously cloned and ...