Browsing Magister Scientiae - MSc (Biotechnology) by Title
Now showing items 103-122 of 263
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Factors associated with participation in physical activity among adults with diabete mellitus in Kigali, Rwanda
(2008)The present study aimed to examine the demographic, social and health-related factors that are associated with levels of physical activity participation among adults with diabetes mellitus in Kigali, Rwanda. -
The feasibility of high resolution, three-dimensional reconstruction of metal-coated surfaces in structural biology
(2006)Life is an emergent property of a complex network of interacting cellular-machines. Three-dimensional (3D), cellular structure captured at supra-atomic resolution has the potential to revolutionise our understanding of the ... -
Forensic identification of six of Tanzanian populations using the extended haplotype markers
(University of the Western Cape, 2011)The aim of the present study was to evaluate the power of discrimination and genetic (diversity) parameters in the Y chromosome extended haploytpe markers in populations of Tanzania for forensic and populations studies. ... -
Functional analysis of miRNA regulated genes in prostate cancer as potential diagnostic molecules
(University of the Western Cape, 2016)Prostate Cancer is the leading cause of cancer-related death in males in the Western world. It is a common biological disease originating from the reproductive system of the male namely, the prostate gland, usually in older ... -
Functional characterisation of a novel ferulic acid esterase from malawian hot spring metagenome
(2011)There has been a decline in the global fossil fuel reserves, due to an increasing demand for petroleum. Biofuels can be used as an alternative source of energy whereby biomass is converted to liquid fuels such as bioethanol. ... -
Functional characterisation of a thermophilic cellulase from a Malawian metagenomic library
(2013)Biofuels are currently recognised as the most viable source of energy to replace depleting fossil fuel reserves, with bioethanol the most popular alternative alcohol fuel. Producing bioethanol from agricultural waste ... -
Gallic acid modulates salt stress tolerance in soybean plants by regulating antioxidant capacity
(University of the Western Cape, 2017)Soybean [Glycine max L (mer)] is one of the top commodity crops in the world including South Africa (de Beer and Prinsloo, 2013). These small yet important podded legumes are a great source of protein and are used in many forms. -
Gene Discovery in Antarctic Dry Valley Soils
(University of the Western Cape, 2008)The metagenomic approach to gene discovery circumvents conventional gene and gene product acquisition by exploiting the uncultured majority of microorganisms in the environment. It was demonstrated in this study that ... -
The genease activity of mung bean nuclease: fact or fiction?
(University of the Western Cape, 2004)The action of Mung Bean Nuclease (MBN) on DNA makes it possible to clone intact gene fragments from genes of the malaria parasite, Plasmodium. This “genease” activity has provided a foundation for further ... -
Genetic analysis of mitochondrial DNA within Southern African populations.
(UWC, 2020)As human beings we are curious about our origin and ancestry. A curiosity has led to an investigation of human evolution and expansion across the world by means of population genetics and phylo-genetics by evaluating a ... -
¹Genetic analysis of red pigmentation in ‘bon rouge’ pears (Pyrus communis L.)
(University of Western Cape, 2014)European pear (Pyrus communis L.) is the third most important fruit in South Africa after citrus and apple. The Agricultural Research Council (ARC) breeding programme seeks to obtain a fully red coloured pear. Sports ... -
Genetic analysis of resistance to apple scab (Venturia inaequalis) in apple (Malus x domestica Borkh)
(University of the Western Cape, 2007)Amongst the many problems facing the apple industry, apple scab is one of the most challenging experienced by producers. This disease is caused by Venturia inaequalis, which causes lesions to develop on both the fruit and ... -
Genetic diversity of the Organic Cation Transporter 1 gene within the Cape Coloured Population
(University of the Western Cape, 2012)The aim of this study was to investigate the genetic diversity of the SLC22A1 gene and to deduce its possible pharmacogenetic implications within the Cape Coloured population of South Africa; a uniquely admixed population ... -
Genome assembly of next-generation sequencing data for the Oryx bacillus : species of the Mycobacterium tuberculosis complex
(University of the Western Cape, 2011)Next generation sequencing (NGS) technology platforms have accelerated ability to produce completed genome assemblies. Recently, collaborators at Tygerberg Medical School outsourced the sequencing of Oryx bacillus, a ... -
The geographical analysis of the mitochondrial DNA control region found in southern African population's by using a bioinformatics approach
(University of the Western Cape, 2020)South Africa’s demographic complexity has been historically shaped by interethnic admixture between the native KhoiSan inhabitants and the Bantu expansion that started 3000 - 5000 YBP and reached South Africa about 1000 ... -
Green Synthesis and characterization of gold Nanoparticles using Green Alga Ulva Lactuca and evaluation of their Catalytric Role
(University of the Western Cape, 2016)Nanoparticles synthesized using typical chemical procedures have associated environmental risks because of the use of hazardous chemicals. With the ever-increasing potential application for nanomaterials, there is a growing ... -
Green synthesis and characterization of silver nanoparticles (AgNPs) from Bulbine frutescens leaf extract and their antimicrobial effects
(University of the Western Cape, 2020)Combating antimicrobial resistant infections caused by nosocomial pathogens poses a major public health problem globally. The widespread use of broad-spectrum antibiotics for the treatment of wound infections has led to ... -
Green synthesis of silver nanoparticles from Indian hawthorn (rhaphiolepis indica) and the investigation of their antimicrobial, antioxidant and cytotoxic effects
(University of Western Cape, 2024-01-08)The global health concern pertaining the rapid spread of antimicrobial resistance (AMR) has led to a rise in mortality rate caused by infectious diseases that have become difficult to treat due to the misuse and lack ... -
Human testis angiotensin-converting enzyme: crystal structure of a glycosylation mutant and investigation of a putative hinge-mechanism by normal mode analysis
(University of the Western Cape, 2004)Human angiotensin-converting enzyme (ACE) is a key enzyme in the regulation of blood pressure via the renin-angiotensin and kallikrein-kinin systems. A number of orally active drugs have been developed over the years ... -
Identification and characterisation of hemicellulases from thermophilic Actinomycetes
(University of the Western Cape, 2010)To ensure the sustainability of bioethanol production, major attention has been directed to develop feedstocks which provide an alternative to food-crop biomass. Lignocellulosic (LC) biomass, which is chiefly composed of ...