Browsing Magister Scientiae - MSc (Biotechnology) by Title
Now showing items 109-128 of 263
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Gallic acid modulates salt stress tolerance in soybean plants by regulating antioxidant capacity
(University of the Western Cape, 2017)Soybean [Glycine max L (mer)] is one of the top commodity crops in the world including South Africa (de Beer and Prinsloo, 2013). These small yet important podded legumes are a great source of protein and are used in many forms. -
Gene Discovery in Antarctic Dry Valley Soils
(University of the Western Cape, 2008)The metagenomic approach to gene discovery circumvents conventional gene and gene product acquisition by exploiting the uncultured majority of microorganisms in the environment. It was demonstrated in this study that ... -
The genease activity of mung bean nuclease: fact or fiction?
(University of the Western Cape, 2004)The action of Mung Bean Nuclease (MBN) on DNA makes it possible to clone intact gene fragments from genes of the malaria parasite, Plasmodium. This “genease” activity has provided a foundation for further ... -
Genetic analysis of mitochondrial DNA within Southern African populations.
(UWC, 2020)As human beings we are curious about our origin and ancestry. A curiosity has led to an investigation of human evolution and expansion across the world by means of population genetics and phylo-genetics by evaluating a ... -
¹Genetic analysis of red pigmentation in ‘bon rouge’ pears (Pyrus communis L.)
(University of Western Cape, 2014)European pear (Pyrus communis L.) is the third most important fruit in South Africa after citrus and apple. The Agricultural Research Council (ARC) breeding programme seeks to obtain a fully red coloured pear. Sports ... -
Genetic analysis of resistance to apple scab (Venturia inaequalis) in apple (Malus x domestica Borkh)
(University of the Western Cape, 2007)Amongst the many problems facing the apple industry, apple scab is one of the most challenging experienced by producers. This disease is caused by Venturia inaequalis, which causes lesions to develop on both the fruit and ... -
Genetic diversity of the Organic Cation Transporter 1 gene within the Cape Coloured Population
(University of the Western Cape, 2012)The aim of this study was to investigate the genetic diversity of the SLC22A1 gene and to deduce its possible pharmacogenetic implications within the Cape Coloured population of South Africa; a uniquely admixed population ... -
Genome assembly of next-generation sequencing data for the Oryx bacillus : species of the Mycobacterium tuberculosis complex
(University of the Western Cape, 2011)Next generation sequencing (NGS) technology platforms have accelerated ability to produce completed genome assemblies. Recently, collaborators at Tygerberg Medical School outsourced the sequencing of Oryx bacillus, a ... -
The geographical analysis of the mitochondrial DNA control region found in southern African population's by using a bioinformatics approach
(University of the Western Cape, 2020)South Africa’s demographic complexity has been historically shaped by interethnic admixture between the native KhoiSan inhabitants and the Bantu expansion that started 3000 - 5000 YBP and reached South Africa about 1000 ... -
Green Synthesis and characterization of gold Nanoparticles using Green Alga Ulva Lactuca and evaluation of their Catalytric Role
(University of the Western Cape, 2016)Nanoparticles synthesized using typical chemical procedures have associated environmental risks because of the use of hazardous chemicals. With the ever-increasing potential application for nanomaterials, there is a growing ... -
Green synthesis and characterization of silver nanoparticles (AgNPs) from Bulbine frutescens leaf extract and their antimicrobial effects
(University of the Western Cape, 2020)Combating antimicrobial resistant infections caused by nosocomial pathogens poses a major public health problem globally. The widespread use of broad-spectrum antibiotics for the treatment of wound infections has led to ... -
Green synthesis of silver nanoparticles from Indian hawthorn (rhaphiolepis indica) and the investigation of their antimicrobial, antioxidant and cytotoxic effects
(University of Western Cape, 2024-01-08)The global health concern pertaining the rapid spread of antimicrobial resistance (AMR) has led to a rise in mortality rate caused by infectious diseases that have become difficult to treat due to the misuse and lack ... -
Human testis angiotensin-converting enzyme: crystal structure of a glycosylation mutant and investigation of a putative hinge-mechanism by normal mode analysis
(University of the Western Cape, 2004)Human angiotensin-converting enzyme (ACE) is a key enzyme in the regulation of blood pressure via the renin-angiotensin and kallikrein-kinin systems. A number of orally active drugs have been developed over the years ... -
Identification and characterisation of hemicellulases from thermophilic Actinomycetes
(University of the Western Cape, 2010)To ensure the sustainability of bioethanol production, major attention has been directed to develop feedstocks which provide an alternative to food-crop biomass. Lignocellulosic (LC) biomass, which is chiefly composed of ... -
Identification and characterisation of novel cellulolytic genes using metagenomics
(University of the Western Cape, 2010)Metagenomics has been successfully used to discover novel enzymes from uncultured microorganisms in the environment. In this study, metagenomic DNA from a Malawian hot spring soil sample was used to construct a fosmid ... -
Identification and characterisation of potential virulence genes of Salmonella from rooibos tea
(University of the Western Cape, 2015)The aim of this study was to investigate the presence of Salmonella in the tea processing environment, to identify and detect potential virulence genes isolated from Salmonella in the tea, and to determine the antibiotic ... -
Identification and characterisation of sorghum bicolor heme oxygenase-1 (sbho1) gene and its role in conferring biotic and abiotic stress tolerance to plants
(University of the Western Cape, 2019)Biotic and abiotic stresses such as herbivore attack, pathogen infection, salinity, drought, cold, heat and UV radiation, are unfavourable conditions that affect plant growth and productivity globally (Fedoroff et al., ... -
Identification and characterization of microorganisms associated with marine macroalgae Splachnidium rugosum
(University of the Western Cape, 2014)Marine macroalgae are known to carry diverse bacterial communities which interact with their hosts in both harmful and beneficial ways. Algae hosts provide the bacteria with a rich source of carbon in the form of carbohydrate ... -
Identification and validation of micrornas for diagnosing type 2 diabetes : an in silico and molecular approach
(University of the Western Cape, 2015)Type 2 diabetes mellitus (T2DM), a metabolic disease characterized by chronic hyperglycemia, is the most prevalent form of diabetes globally, affecting approximately 95 % of the total number of people with diabetes i.e. ... -
Identification and validation of putative therapeutic and diagnostic antimicrobial peptides against HIV: An in silico approach
(University of the Western Cape, 2013)Background: Despite the effort of scientific research on HIV therapies and to reduce the rate of HIV infection, AIDS still remains one of the major causes of death in the world and mostly in Sub-Saharan Africa. To date, ...