Browsing Magister Scientiae - MSc (Biotechnology) by Title
Now showing items 151-170 of 270
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Improvement of cell-surface adhered cellulase activities in recombinant strains of Saccharomyces cerevisiae engineered for consolidated bioprocessing
(University of Western Cape, 2021)Consolidated bioprocessing (CBP), in which a single organism in a single reactor is responsible for the conversion of pretreated lignocellulosic biomass to bioethanol, remains an attractive option for production of commodity ... -
Improving Evaporation Rate of Mine Wastewater
(University of the Western Cape, 2018)The treatment of mine water at the eMalahleni Water Reclamation Plant (EWRP) results in the production of large volumes of brine. Different brine management methods have been applied to dispose the brine but the evaporation ... -
The in vitro detection and measurement of the unfolded protein response in Saccharomyces cerevisiae
(University of the Western Cape, 2018)Bioethanol is currently the most widely used biofuel and can be used as a direct replacement for current fossil fuel based transportation fuels. Consolidated bioprocessing (CBP), in which bioethanol is produced in a single ... -
In vitro evaluation of Leonotis leonurus to validate its potential as an alternative anti-diabetic drug
(University of the Western Cape, 2022)Africa is a rich source of medicinal plants with South Africa being known as a country with a strong history of traditional healing, which masses a variety of approximately 30 000 flowering plants and accounting for ... -
In vitro investigation of putative interactions between the RING finger domain of Retinoblastoma Binding Protein 6 (RBBP6) and various substrates
(University of the Western Cape, 2015)Retinoblastoma Binding Protein 6 (RBBP6) is a RING finger-containing protein which plays a critical role in the 3'-end processing of mRNA transcripts. It is a constituent of the human pre-mRNA processing complex but also ... -
In vitro investigation of the ubiquitination and degradation of p53 by Murine Double Minute 2 (MDM2) and Retinoblastoma Binding Protein 6 (RBBP6)
(University of the Western Cape, 2015)P53 is one of the most important tumour suppressor proteins in the body which protects the cell against the tumourigenic effects of DNA damage by initiating processes such as apoptosis, senescence and cell cycle arrest. ... -
Increasing ethanol tolerance through the heterologous expression of the geobacillus thermoglucosiadius heat-shock proteins (GroEL/GroES) in an escherichia coli host
(University of the Western Cape, 2012)Due to economic and environmental concerns associated with use of fossil fuels, humanity is seeking alternative fuels. Ethanol is one of the alternative fuels produced commercially. Current ethanol production technologies ... -
Influence of a selected endophyte consortium on salinity responses in Medicago sativa
(University of Western Cape, 2022)Salinity is one of the major limiting factors to crop production, which consequently contributes to the risk of reduced food security. Among other factors, food security depends on availability of sufficient and nutritious ... -
The Internal Validation and Casework Application of MiniSTR Systems
(University of the Western Cape, 2008)The objective of the study was to conduct an internal validation on miniSTR systems and apply it to cases received from the South African Missing Persons Task Team (SAMPTT). This was prompted by the fact that miniSTR systems ... -
Investigating the effect of particle size on the antibacterial activity of gold nanoparticles
(University of the Western Cape, 2017)The increase of antibiotic- and/or multidrug-resistant bacteria has become a major global challenge. Killing of antibiotic-resistant bacteria requires a high dose of multiple, expensive drugs, which possess unfavourable ... -
Investigating the effect of particle size on the antibacterial activity of gold nanoparticles
(University of the Western Cape, 2017)The increase of antibiotic- and/or multidrug-resistant bacteria has become a major global challenge. Killing of antibiotic-resistant bacteria requires a high dose of multiple, expensive drugs, which possess unfavourable ... -
Investigating the functional interaction of transcription regulator CarD of Mycobacterium tuberculosis with Ribonucleic Acid Polymerase
(University of the Western Cape, 2014)Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). TB mainly affects lungs of patients but other parts of the body can also be affected. It kills approximately 2 million people annually. ... -
Investigating the functional interaction of transcription regulator card of mycobacterium tuberculosis with ribonucleic acid polymerase
(2013)Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). TB mainly affects lungs of patients but other parts of the body can also be affected. It kills approximately 2 million people annually. ... -
Investigation into the role of DWNN in cell death
(University of the Western Cape, 2004)Many genes are activated to influence the self-destruction programme of the cell. This programme entails synchronised instigation and implementation of numerous subprograms. The arrival of gene targeting aided in the ... -
Investigation of protein-metal ion and protein-protein interactions using mass spectrometry and nuclear magnetic spectroscopy
(University of Western Cape, 2014)Protein-protein interaction networks provide a global picture of cellular function and biological processes. Some proteins act as hub proteins, highly connected to others, whereas some others have few interactions. The ... -
Investigation of protein-protein interactions involving retinoblastoma binding protein 6 using immunoprecipitation and nuclear magnetic resonance spectroscopy
(University of Western Cape, 2019)Retinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa multi-domain protein that has been shown to play a role in mRNA processing, cell cycle arrest and apoptosis. RBBP6 interacts with tumour suppressor proteins such as ... -
Investigation of protein-protein interactions involving Retinoblastoma Binding Protein 6 using immunoprecipitation and Nuclear Magnetic Resonance Spectroscopy
(University of the Western Cape, 2019)Retinoblastoma Binding Protein 6 (RBBP6) is a 200 KDa multi-domain protein that has been shown to play a role in mRNA processing, cell cycle arrest and apoptosis. RBBP6 interacts with tumour suppressor proteins such as ... -
Investigation of South African estuarine microbial species and genome diversity
(University of the Western Cape, 2006)A study of the microbial diversity in sediments of the Great Berg River estuary is carried out using modern molecular phylogenetic methods. The aim of this study was to determine the effect of (pollution by) the effluents ... -
Investigation of the anti-obesity effects of citrate-capped gold nanoparticles on 3T3-L1 cells and their genetic profiling
(University of the Western Cape, 2023)The incidence and prevalence of obesity and its related diseases has nearly tripled and is increasing at an alarming rate worldwide. Several modern methods for the management and treatment of obesity are available, with ... -
Investigation of the auto-ubiquitination and ubiquitination potentials of Retinoblastoma binding protein 6 and its binding to p53
(University of Western Cape, 2019)Retinoblastoma Binding Protein 6 (RBBP6) is a 200 kDa human protein known to play an essential role in mRNA 3’-end processing, as well as functioning as an E3 ligase to catalyze ubiquitination and suppression of p53 and ...